γH2AX和ATM与内源性氧化剂所致DNA损伤关系的研究进展
γH2AX화ATM여내원성양화제소치DNA손상관계적연구진전
Progress in the research of relationship between γH2AX, ATM and DNA damage by endogenous oxidants
  • 万方数据
    基础医学与临床 기출의학여림상
    BASIC MEDICAL SCIENCES AND CLINICS
    2010年 4期 437-441 ,共5页

    赵晋%郭忠%马建秀

    조진%곽충%마건수

    内源性氧化剂%γH2AX%ATM 內源性氧化劑%γH2AX%ATM
    내원성양화제%γH2AX%ATM
    endogenous oxidants%γH-2AX%ATM
    本文综述了正常细胞及肿瘤细胞系中内源性氧化剂所致的磷酸化ATM(CAA)和γH2AX(CHP)的形成与表达;同时综述了各种影响因子和生长条件对CAA和CHP表达的影响.
    본문종술료정상세포급종류세포계중내원성양화제소치적린산화ATM(CAA)화γH2AX(CHP)적형성여표체;동시종술료각충영향인자화생장조건대CAA화CHP표체적영향.
    This review describes the observations that constitutive ATM activation (CAA) and H2AX phosphoryla-tion (CHP) caused by endogenous oxidants in normal cells as well in tumor cell lines.This review also reported the findings on differences in CAA and CHP on the effects of several agents and growth conditions.
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