CAJ | 학술논문

目的探讨单纯夜间高血压与左室肥厚的关系.方法在浙江省景宁县14个村的居民中,记录24 h血压和12导联心电图.结果 647例受检者中单纯夜间高血压[平均血压≥120/70mm Hg(1 mm Hg=0.133 kPa)]有72例(11.1%).夜间和白天的收缩压或舒张压都是左室肥厚的独立影响因素(P<0.01).但单纯夜间高血压患者左室肥厚的患病率(23.6%)与正常血压者(17.4%)相比,差异无统计学意义(P=0.24).结论在本横断面研究中,单纯夜间高血压与用心电图诊断的左室肥厚没有显著独立关联.
목적 탐토단순야간고혈압여좌실비후적관계.방법 재절강성경저현14개촌적거민중,기록24 h혈압화12도련심전도.결과 647례수검자중단순야간고혈압[평균혈압≥120/70mm Hg(1 mm Hg=0.133 kPa)]유72례(11.1%).야간화백천적수축압혹서장압도시좌실비후적독립영향인소(P<0.01).단단순야간고혈압환자좌실비후적환병솔(23.6%)여정상혈압자(17.4%)상비,차이무통계학의의(P=0.24).결론 재본횡단면연구중,단순야간고혈압여용심전도진단적좌실비후몰유현저독립관련.
Objective To investigate the relationship between isolated nocturnal hypertension and left ventricular hypertrophy. Methods In the inhabitants of 14 villages in Jingning County, Zhejiang Province, we performed 24-hour ambulatory blood pressure monitoring with SpaceLab monitors and measured 12-lead resting electrocardiogram using an electronic recording system of GE company, Left ventrieular hypertrophy was diagnosed with the criteria of Sokolow-Lyon voltage amplitude and Cornell product. Isolated nocturnal hypertension was defined as a nighttime ( from 22:00 to 4:00) blood pressure of ≥ 120/70 mm Hg( 1 mm Hg = 0. 133 kPa). Isolated daytime ( from 8:00 to 18:00) hypertension was a diurnal blood pressure of ≥ 135/85 nun Hg. When both conditions were present or absent, subjects were classified either as having combined day-night hypertension or as normotensive on ambulatory measurement. Analysis of variance and multiple regressions were used for statistical analysis. Results 647 participants (53.9% being female,average age 47. 8 years) included 72 patients with isolated nocturnal hypertension, 33 with isolated daytime hypertension and 248 with day-night sustained hypertension. Compared with normotensive subjects, patients with isolated nocturnal hypertension and day-night sustained hypertension had a higher Sokoiow-Lyon voltage amplitude and Comell product. However, after adjustment for sex, age, body mass index, drinking and smoking habits, serum total cholesterol, fasting blood glucose and the use of antihypertensive drugs, only day-night hypertensive patients had a significantly higher Sokolow-Lyon voltage (32. 8 mV, P =0. 0003 ) and Cornell product (1371 mV×ms, P =0.0004) than normotensive subjects (29.0 mV, 1114 mV×ms).Regardless of whether Sokolow-Lyon or Cornell criteria were used, both nighttime and daytime systolic and diastolic blood pressure were independent risk factors of left ventricular hypertrophy (P < 0. 01 ). However,the prevalence of left ventricular hypertrophy in patients with isolated nocturnal hypertension ( 23.6% ) study was not statistically different from that in normotensives ( 17.4%, P = 0. 24). Conclusion In our current cross-sectional study, isolated nocturnal hypertension was not independently related to left ventricular hypertrophy diagnosed with ECG criteria.