CAJ | 학술논문

目的探讨特纳综合征合并脊柱关节炎的临床特点,以提高对该病的认识.方法报道我院诊治的1例特纳综合征合并脊柱关节炎患者,并结合国内外报道的5例患者,分析其临床表现、实验室检查及影像学的特点.结果 6例患者均为女性,平均年龄(27±5)岁.其中2例为脊柱关节炎,3例为强直性脊柱炎.1例为银屑病关节炎.5例出现外周关节炎,其中4例为首发症状.2例出现炎性背痛.4例存在椎体活动受限.3例存在关节内、外翻畸形.6例染色体核型均为45,XO.6例均存在骨质疏松.结论特纳综合征可合并脊柱关节炎,其特点是外周关节炎、骨质疏松、骨关节发育异常.
목적 탐토특납종합정합병척주관절염적림상특점,이제고대해병적인식.방법 보도아원진치적1례특납종합정합병척주관절염환자,병결합국내외보도적5례환자,분석기림상표현、실험실검사급영상학적특점.결과 6례환자균위녀성,평균년령(27±5)세.기중2례위척주관절염,3례위강직성척주염.1례위은설병관절염.5례출현외주관절염,기중4례위수발증상.2례출현염성배통.4례존재추체활동수한.3례존재관절내、외번기형.6례염색체핵형균위45,XO.6례균존재골질소송.결론 특납종합정가합병척주관절염,기특점시외주관절염、골질소송、골관절발육이상.
Objective To investigate the clinical characteristics of Turner syndrome in patients with spondyloarthropathy.Methods Six patients from our hospital were included and the clinical manifestations,laboratory parameters and imaging presentations were analyzed retrospectively and the relevant literature were reviewed.Results The mean age of these 6 cases was (27±5) years.Two cases were spondyloarthropathy,3 cases were ankylosing spondylitis,1 was psoriatic arthritis.Five cases were complicated with peripheral arthriris,2 cases were complicated with inflammatory back pain,4 cases had vertebral activity limitation,3 cases had joint deformity.The karyotype of 6 cases was 45,XO.Six cases were complicated with osteoporosis.Conclusion Turner syndrome can be presented with spondyloarthropathy,arthritis,osteoporosis.Dysplasia of bone is common.