中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2012年
4期
413-417
,共5页
黄启涛%钟梅%王晨虹%陈敦金%刘正平%黎静%王硕石%汪丽萍%宋天蓉%郭雪菁%冷灵芝%罗小华%刘建%秦竞霞%梁海英%刘丽娜
黃啟濤%鐘梅%王晨虹%陳敦金%劉正平%黎靜%王碩石%汪麗萍%宋天蓉%郭雪菁%冷靈芝%囉小華%劉建%秦競霞%樑海英%劉麗娜
황계도%종매%왕신홍%진돈금%류정평%려정%왕석석%왕려평%송천용%곽설정%랭령지%라소화%류건%진경하%량해영%류려나
深静脉血栓%颅内静脉血栓%发生率%危险因素
深靜脈血栓%顱內靜脈血栓%髮生率%危險因素
심정맥혈전%로내정맥혈전%발생솔%위험인소
Deep vein thrombosis%Cerebral venous thrombosis%Prevalence%Risk factors
目的 探讨广东省不同地域孕产妇围生期栓塞性疾病发病情况、流行病学特征及相关高危因素.方法 回顾性调查2005年1月至2010年6月广东省珠三角及粤东、西、北地区13家三甲医院共169218名孕产妇病历资料,分析妊娠期或产褥期栓塞性疾病的发病率及其流行病学特征.结果 (1)169 218名孕产妇中,栓塞性疾病共201例,发生率为1.3‰,其中妊娠或产褥期合并下肢深静脉血栓形成(DVT) 128例,合并颅内静脉窦血栓形成(CVT)68例,合并肺栓塞5例,发生率分别为0.8‰、0.4％、0.02‰.(2)珠三角地区孕产妇DVT发生前5位高危因素主要为既往血栓病史或血栓家族史、妊娠合并症、妊娠合并内科疾病、卧床时间＞3d、孕期体重增长＞15kg;粤东、西、北地区孕产妇DVT发生前5位高危因素主要为孕期体重增长＞15kg、卧床时间＞3d、子痫前期、剖宫产手术、妊娠合并症.珠三角地区孕产妇CVT发生前5位高危因素主要为子痫、子痫前期、妊娠合并症、卧床时间＞3 d、既往血栓病史或血栓家族史；粤东、西、北地区孕产妇CVT发生前5位高危因素主要为子痫、子痫前期、高龄或低龄妊娠、孕期体重增长＞15 kg、妊娠合并症.结论 不同地域围生期栓塞性疾病的发病率及危险因素存在着一定差异；对不同地域栓塞性疾病发病特点及发病高危因素采取有效措施,是预防和降低疾病发生的重要手段.
目的 探討廣東省不同地域孕產婦圍生期栓塞性疾病髮病情況、流行病學特徵及相關高危因素.方法 迴顧性調查2005年1月至2010年6月廣東省珠三角及粵東、西、北地區13傢三甲醫院共169218名孕產婦病歷資料,分析妊娠期或產褥期栓塞性疾病的髮病率及其流行病學特徵.結果 (1)169 218名孕產婦中,栓塞性疾病共201例,髮生率為1.3‰,其中妊娠或產褥期閤併下肢深靜脈血栓形成(DVT) 128例,閤併顱內靜脈竇血栓形成(CVT)68例,閤併肺栓塞5例,髮生率分彆為0.8‰、0.4％、0.02‰.(2)珠三角地區孕產婦DVT髮生前5位高危因素主要為既往血栓病史或血栓傢族史、妊娠閤併癥、妊娠閤併內科疾病、臥床時間＞3d、孕期體重增長＞15kg;粵東、西、北地區孕產婦DVT髮生前5位高危因素主要為孕期體重增長＞15kg、臥床時間＞3d、子癇前期、剖宮產手術、妊娠閤併癥.珠三角地區孕產婦CVT髮生前5位高危因素主要為子癇、子癇前期、妊娠閤併癥、臥床時間＞3 d、既往血栓病史或血栓傢族史；粵東、西、北地區孕產婦CVT髮生前5位高危因素主要為子癇、子癇前期、高齡或低齡妊娠、孕期體重增長＞15 kg、妊娠閤併癥.結論 不同地域圍生期栓塞性疾病的髮病率及危險因素存在著一定差異；對不同地域栓塞性疾病髮病特點及髮病高危因素採取有效措施,是預防和降低疾病髮生的重要手段.
목적 탐토광동성불동지역잉산부위생기전새성질병발병정황、류행병학특정급상관고위인소.방법 회고성조사2005년1월지2010년6월광동성주삼각급월동、서、북지구13가삼갑의원공169218명잉산부병력자료,분석임신기혹산욕기전새성질병적발병솔급기류행병학특정.결과 (1)169 218명잉산부중,전새성질병공201례,발생솔위1.3‰,기중임신혹산욕기합병하지심정맥혈전형성(DVT) 128례,합병로내정맥두혈전형성(CVT)68례,합병폐전새5례,발생솔분별위0.8‰、0.4％、0.02‰.(2)주삼각지구잉산부DVT발생전5위고위인소주요위기왕혈전병사혹혈전가족사、임신합병증、임신합병내과질병、와상시간＞3d、잉기체중증장＞15kg;월동、서、북지구잉산부DVT발생전5위고위인소주요위잉기체중증장＞15kg、와상시간＞3d、자간전기、부궁산수술、임신합병증.주삼각지구잉산부CVT발생전5위고위인소주요위자간、자간전기、임신합병증、와상시간＞3 d、기왕혈전병사혹혈전가족사；월동、서、북지구잉산부CVT발생전5위고위인소주요위자간、자간전기、고령혹저령임신、잉기체중증장＞15 kg、임신합병증.결론 불동지역위생기전새성질병적발병솔급위험인소존재착일정차이；대불동지역전새성질병발병특점급발병고위인소채취유효조시,시예방화강저질병발생적중요수단.
Objective To investigate the prevalence and major risk factors of peripartum thromboembolic disease in different regions of Guangdong province.Methods Data from 169 218pregnant women in different regions of Guangdong province from January 2005 to June 2010 were analyzed retrospectively.The prevalence and epidemiological characteristics of thromboembolic disease during pregnancy or puerperium were investigated.Results Of the studied population,( 1 )20 l cases ( 1.3‰ ) suffered from thromboembolic disease during pregnancy or puerperium including 128 cases of deep vein thrombosis (DVT),68 cases of cerebral venous thrombosis (CVT) and 5pulmonary embolism,the prevalence rates were 0.8‰,0.4‰,and 0.02‰ respectively.(2) Risk factors in different regions showed that,in the Pearl River Delta area,the major risk factors for DVT would include previous or family history of thrombosis,pregnancy complications,with medically involved diseases,prolonged bed rest and pregnancy weight gain ＞ 15 kg etc.While in castern,western,northern parts of Guangdong,the major risk factors for DVT would include pregnancy weight gain ＞ 15 kg,prolonged bed rest,preeclampsia,cesarean section and complications during pregnancy.In Pearl River Delta region,the major risk factors for CVT would include eclampsia,preeclampsia,pregnancy complications,prolonged bed rest ＞3 days,past history or family history of thrombosis.While eclampsia,preeclampsia,advanced age or younger age,pregnancy weight gain ＞15 kg,complications during pregnancy were the major risk factors for CVT in the eastern,western or northem parts of Guangdong.Conclusion Prevalence and major risk factors of peripartum thromboembolic disease in different regions of Guangdong were different.It was crucial to take effective measures in pregnant women with different epidemiological characteristics and risk factors to prevent and reduce the incidence of peripartum thromboembolic disease.
