CAJ | 학술논문

目的探讨影响颅内静脉窦血栓形成(CVST)后昏迷患者预后的相关因索。方法对梧州市工人医院神经内科自2001年2月至2010年2月收治的以昏迷就诊或在入院6h内出现不同程度昏迷的30例CVST患者的临床资料进行回顾性分析。结果随访0.5～10年，本组患者中12例无明显颅内压增高、脑深静脉血栓及相关脑血管意外,8例死亡，2例重残，8例遗留不同程度的偏瘫或智力语言障碍。CVST后昏迷患者伴有中枢神经系统感染、恶性肿瘤、脑深静脉血栓形成、癫痫及颅内出血等改变时患者预后差，其中恶性肿瘤患者重残或死亡率高达50％。结论CVST后发生昏迷的患者预后差，病死率高，及早诊治并合理治疗有助于改善预后。
목적탐토영향로내정맥두혈전형성(CVST)후혼미환자예후적상관인색。 방법대오주시공인의원신경내과자2001년2월지2010년2월수치적이혼미취진혹재입원6h내출현불동정도혼미적30례CVST환자적림상자료진행회고성분석。 결과수방0.5～10년，본조환자중12례무명현로내압증고、뇌심정맥혈전급상관뇌혈관의외,8례사망，2례중잔，8례유류불동정도적편탄혹지력어언장애。CVST후혼미환자반유중추신경계통감염、악성종류、뇌심정맥혈전형성、전간급로내출혈등개변시환자예후차，기중악성종류환자중잔혹사망솔고체50％。 결론CVST후발생혼미적환자예후차，병사솔고，급조진치병합리치료유조우개선예후。
Objective To investigate the factors affecting the prognosis of coma patients with cerebral venous sinus thrombosis (CVST). Methods We retrospectively analyzed the clinical data of 30 coma patients with CVST, admitted to our hospital from February 2001 to February 2010, including patients in coma on admission and patients turned to be in the different degrees' coma after admission within 6 h. Results Twelve patients had no increased intracranial pressure, cerebral venous sinus thrombosis or related symptoms with cerebral vascular, 8 patients died and 2 were seriously disable; 8suffered from sequel of different degrees ofhemiplegia or mental language barriers. The CVST patients associated with infection in central nervous system, cancer, cerebral deep venous thrombosis, epilepsy and intracranial hemorrhage were with poor prognosis, enjoying a possibility of mortality and severe disability up to 50％. Conclusion Coma patients with CVST were with poor prognosis and high mortality; early diagnosis and appropriate treatment might help to improve the prognosis.