中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2009年
25期
1749-1752
,共4页
张红霞%贾丽丽%侯旭宏%陆俊茜%陆惠娟%杜颉%顾惠林%贾伟平
張紅霞%賈麗麗%侯旭宏%陸俊茜%陸惠娟%杜頡%顧惠林%賈偉平
장홍하%가려려%후욱굉%륙준천%륙혜연%두힐%고혜림%가위평
糖尿病视网膜病变%横断面研究%危险因素
糖尿病視網膜病變%橫斷麵研究%危險因素
당뇨병시망막병변%횡단면연구%위험인소
Diabetic retinopathy%Cross-sectional studies%Risk factors
目的 了解上海社区糖尿病前期(IGR)及糖尿病(DM)人群视网膜病变(DR)的患病率及相关危险因素.方法 于2005年6月至2006年3月对在上海市华阳及曹杨两个社区代谢综合征现况调查中获得的IGR和DM病人(共1300例)进行DR筛查,将完成调查并具有完整数据的642例病人(DM者391例,IGR者251例)纳入本次分析,其中男312例,女330例,平均年龄(65±13)岁.视网膜病变采用Canon CR-DGi免散瞳眼底照相机拍照法,并根据国际临床糖尿病视网膜病变严重程度的分级标准诊断.结果 社区DM病人DR患病率为19.9%(78例),其中轻、中、重度及增殖性DR的患病率依次为12.0%、5.1%、2.3%和0.5%;IGR人群的DR患病率为8.0%(20例).Logistic回归结果 见到糖尿病病程、糖化血红蛋白是DM病人合并DR的独立危险因素.结论 上海社区高血糖人群DR的患病率较高,IGR人群已有DR发生.病程长、血糖控制差均可增加DM病人发生DR的危险.
目的 瞭解上海社區糖尿病前期(IGR)及糖尿病(DM)人群視網膜病變(DR)的患病率及相關危險因素.方法 于2005年6月至2006年3月對在上海市華暘及曹楊兩箇社區代謝綜閤徵現況調查中穫得的IGR和DM病人(共1300例)進行DR篩查,將完成調查併具有完整數據的642例病人(DM者391例,IGR者251例)納入本次分析,其中男312例,女330例,平均年齡(65±13)歲.視網膜病變採用Canon CR-DGi免散瞳眼底照相機拍照法,併根據國際臨床糖尿病視網膜病變嚴重程度的分級標準診斷.結果 社區DM病人DR患病率為19.9%(78例),其中輕、中、重度及增殖性DR的患病率依次為12.0%、5.1%、2.3%和0.5%;IGR人群的DR患病率為8.0%(20例).Logistic迴歸結果 見到糖尿病病程、糖化血紅蛋白是DM病人閤併DR的獨立危險因素.結論 上海社區高血糖人群DR的患病率較高,IGR人群已有DR髮生.病程長、血糖控製差均可增加DM病人髮生DR的危險.
목적 료해상해사구당뇨병전기(IGR)급당뇨병(DM)인군시망막병변(DR)적환병솔급상관위험인소.방법 우2005년6월지2006년3월대재상해시화양급조양량개사구대사종합정현황조사중획득적IGR화DM병인(공1300례)진행DR사사,장완성조사병구유완정수거적642례병인(DM자391례,IGR자251례)납입본차분석,기중남312례,녀330례,평균년령(65±13)세.시망막병변채용Canon CR-DGi면산동안저조상궤박조법,병근거국제림상당뇨병시망막병변엄중정도적분급표준진단.결과 사구DM병인DR환병솔위19.9%(78례),기중경、중、중도급증식성DR적환병솔의차위12.0%、5.1%、2.3%화0.5%;IGR인군적DR환병솔위8.0%(20례).Logistic회귀결과 견도당뇨병병정、당화혈홍단백시DM병인합병DR적독립위험인소.결론 상해사구고혈당인군DR적환병솔교고,IGR인군이유DR발생.병정장、혈당공제차균가증가DM병인발생DR적위험.
Objective To determine the prevalence and risk factors of diabetic retinopathy (DR) in the Diabetes Mellitus (DM) and impaired glucose regulation (IGR) population in Shanghai Community. Methods DR screening after the epidemiologic study of metabolic syndrome in Huayang and Canyang Community , Shanghai was conducted among 1300 patients with DM or IGR during June 2005 and March 2006, Digital non-mydriatic fundus photography was performed for each eye in all subjects. Other factors, including diabetes related history, BMI, WHR, fasting plasma glucose, HbAlc, serum lipid and blood pressure were also assessed. 642 patients,312 males and 330 females, aged 65 ± 13, with complete data were enrolled into the analysis. Results The prevalence of DR was 19. 9% in the diabetic population, and the prevalence of mild, moderate, severe non-proliferative retinopathy and proliferative retinopathy was 12. 0%, 5. 1%, 2. 3% and 0. 5%, respectively; the prevalence of DR in IGR reached 8. 0%. Logistic regression analysis revealed that HbA1c level and diabetes duration were both independently associated with diabetic retinopathy. Conclusion The prevalence of DR was high in both DM and IGR population. Bad blood glucose control and long diabetes duration both increased occurrence of DR.
