中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2012年
1期
44-46
,共3页
癫痫%C-反应蛋白%发作程度
癲癇%C-反應蛋白%髮作程度
전간%C-반응단백%발작정도
Epilepsy%C - reactive protein%Seizure severity
目的 探讨癫痫患者发作严重程度与其血清C-反应蛋白(CRP)水平的相关性.方法 197倒癫痫患者药物治疗后,分为无发作组(n=70)、轻度发作组(n=48)、中度发作组(n=50)和重度发作组(n=29),测定197例患者静息期血清CRP水平.结果 无发作组、轻度发作组、中度发作组和重度发作组患者血清CRP分别为(1.44±0.88) mg/L、(2.87±0.18) mg/L、(5.34±0.20) mg/L、(9.63±0.64) mg/L,四组间血清CRP水平总体差异有统计学意义(F=179.35,P＜0.01)；癫痫发作严重程度与血清CRP水平呈正相关性(相关系数rs=0.083,P＜ 0.01).结论 癫痫发作频度越高,其血清CRP水平越高；血清CRP水平可能是预测癫痫发作严重程度的一个指标.
目的 探討癲癇患者髮作嚴重程度與其血清C-反應蛋白(CRP)水平的相關性.方法 197倒癲癇患者藥物治療後,分為無髮作組(n=70)、輕度髮作組(n=48)、中度髮作組(n=50)和重度髮作組(n=29),測定197例患者靜息期血清CRP水平.結果 無髮作組、輕度髮作組、中度髮作組和重度髮作組患者血清CRP分彆為(1.44±0.88) mg/L、(2.87±0.18) mg/L、(5.34±0.20) mg/L、(9.63±0.64) mg/L,四組間血清CRP水平總體差異有統計學意義(F=179.35,P＜0.01)；癲癇髮作嚴重程度與血清CRP水平呈正相關性(相關繫數rs=0.083,P＜ 0.01).結論 癲癇髮作頻度越高,其血清CRP水平越高；血清CRP水平可能是預測癲癇髮作嚴重程度的一箇指標.
목적 탐토전간환자발작엄중정도여기혈청C-반응단백(CRP)수평적상관성.방법 197도전간환자약물치료후,분위무발작조(n=70)、경도발작조(n=48)、중도발작조(n=50)화중도발작조(n=29),측정197례환자정식기혈청CRP수평.결과 무발작조、경도발작조、중도발작조화중도발작조환자혈청CRP분별위(1.44±0.88) mg/L、(2.87±0.18) mg/L、(5.34±0.20) mg/L、(9.63±0.64) mg/L,사조간혈청CRP수평총체차이유통계학의의(F=179.35,P＜0.01)；전간발작엄중정도여혈청CRP수평정정상관성(상관계수rs=0.083,P＜ 0.01).결론 전간발작빈도월고,기혈청CRP수평월고；혈청CRP수평가능시예측전간발작엄중정도적일개지표.
Objective To investigate the associated- relationship between serum C -reactive protein (CRP) and seizure severity in adult epilepsy patients.Methods One hundred and ninety- seven epilepsy patients after drug therapy were divided into 4 groups:non -epileptic seizure group( n =70),mild seizure group ( n =48 ),moderate seizure group ( n =50) and severe seizure group ( n =29 ).The level of CRP in patient serum was measured at resting time of seizure.Results The levels of serum CRP in the 4 groups were ( 1.44 ± 0.88 ) mg/L,( 2.87 ± 0.18 ) mg/L,( 5.34 ± 0.20 ) mg/L and ( 9.63 ±0.64) mg/L,respectively.There were significant differences between the 4 groups tested by ONE - WAY ANOVA (F =179.35,P ＜ 0.01 ).The rank positive associated - relationship existed between the serum CRP level and seizure severity ( rs =0.083,P ＜ 0.01 ).Conclusions The more serious seizure frequency of epilepsy patients,the higher the level of their serum CRP.Serum CRP levels may be a predictor of the severity of epileptic seizures.
