CAJ | 학술논문

目的探讨年轻子宫内膜癌的临床特点及预后.方法对82例确诊的子宫内膜癌患者进行回顾性分析,其中≤45岁31例(年轻组),＞45岁51例(年老组),分析两组患者的临床特点、诊治情况及预后.结果年轻组原发性不孕率和妊娠＜3次率[38.7%(12/31)和74.2%(23/31)]明显高于年老组[3.9%(2/51)和29.4%(15/51)](P＜0.05).两组患者肌层浸润程度比较,差异有统计学意义(P＜0.05);而病理类型、组织学分级、手术病理分期、5年生存率及复发时间比较,差异均无统计学意义(P＞0.05).结论不孕或少孕为年轻子宫内膜癌的发病因素;年轻子宫内膜癌肌层浸润程度较年老患者轻,病理类型、组织学分级、手术病理分期与年老患者相似,但并没有获得比年老者更好的预后.
목적 탐토년경자궁내막암적림상특점급예후.방법 대82례학진적자궁내막암환자진행회고성분석,기중≤45세31례(년경조),＞45세51례(년로조),분석량조환자적림상특점、진치정황급예후.결과 년경조원발성불잉솔화임신＜3차솔[38.7%(12/31)화74.2%(23/31)]명현고우년로조[3.9%(2/51)화29.4%(15/51)](P＜0.05).량조환자기층침윤정도비교,차이유통계학의의(P＜0.05);이병리류형、조직학분급、수술병리분기、5년생존솔급복발시간비교,차이균무통계학의의(P＞0.05).결론 불잉혹소잉위년경자궁내막암적발병인소;년경자궁내막암기층침윤정도교년로환자경,병리류형、조직학분급、수술병리분기여년로환자상사,단병몰유획득비년로자경호적예후.
Objective To investigate the clinical characteristics and prognosis of young patients with endometrial cancer. Methods Eighty-two cases with endometrial cancer were analyzed retrospectively,31 cases in the young group were ≤ 45 years old, and 51 cases in the old group were ＞ 45 years old. The clinical characteristics, diagnosis, treatment and prognosis between the two groups were compared. Results Twelve cases with primary infertility took up 38.7% in the young group,23 cases with less than 3 times of pregnancy occupied 74.2%, and there was no statistical difference,compared with the old group [3.9%(2/51)and 29.4% (15/51)] (P＜0.05). There was statistically significant between the two groups in myometrial invasion (P ＜ 0.05 ); while there was no significance between the two groups in pathological type, histological grade,clinical stage, 5-year survival rate and recurrence period (P＞0.05). Conclusion Infertility or less pregnancy are risk factors for endometrial cancer in the young; the degree of endometrial invasion in the young is more shallow than that in the old; there is no significant difference between the young and the old in pathological type, histological grade and clinical stage; but the prognosis is similar between the young and the old patients.