中国伤残医学
中國傷殘醫學
중국상잔의학
CHINESE JOURNAL OF TRAUMA AND DISABILITY MEDICINE
2014年
12期
17-19
,共3页
探讨%角膜层间分离清刮术%大泡性角膜病变%效果
探討%角膜層間分離清颳術%大泡性角膜病變%效果
탐토%각막층간분리청괄술%대포성각막병변%효과
Explore%CICC%Bullous keratopathy%Effect
目的：研究探讨施行角膜层间分离清刮术（ Corneal interlameller clean curettage ，CICC）治疗大泡性角膜病变（ Bullous keratopathy ，BK）的临床效果。方法：选取我院从2011年4月～2012年5月被确认为BK病患42例，均有角膜上皮不同程度水肿，且失去光泽，有1个或多个大水泡隆起，直径范围约为1～3 mm，部分水泡破裂后，用荧光素染色呈阳性。对其予以角膜层间分离清刮术治疗，观察其疗效以及术后并发症情况，对手术前后病患视力情况记录并进行对比。结果：观察术后疗效及并发症情况，9例病患于手术后2天开始疼痛减轻，15例病患在手术后1周各症状均明显减轻，所有病患于2周内眼部疼痛、畏光以及流泪等症状均解除。病患角膜面平整、光滑，结膜充血情况得以减轻，且角膜逐渐恢复透明。2年之内坚持随访，均无复发及其他明显并发症发生。病患手术前后视力情况对比，手术后病患视力为手动及眼前指数的病患所占比例分别为0％、14．29％，显著低于手术前的47．62％、35．71％。且视力为0．01～0．02及0．03～0．04的病患所占比例分别为59．52％、26．19％，显著高于手术前的16．67％、0％。差异均有统计学意义（均P＜0．05）。结论：CICC治疗BK，疗效显著，可有效清除角膜大泡病变，解除病患疼痛，并能够恢复病患视力，无并发症发生，安全性高，具有积极意义，值得推荐。
目的：研究探討施行角膜層間分離清颳術（ Corneal interlameller clean curettage ，CICC）治療大泡性角膜病變（ Bullous keratopathy ，BK）的臨床效果。方法：選取我院從2011年4月～2012年5月被確認為BK病患42例，均有角膜上皮不同程度水腫，且失去光澤，有1箇或多箇大水泡隆起，直徑範圍約為1～3 mm，部分水泡破裂後，用熒光素染色呈暘性。對其予以角膜層間分離清颳術治療，觀察其療效以及術後併髮癥情況，對手術前後病患視力情況記錄併進行對比。結果：觀察術後療效及併髮癥情況，9例病患于手術後2天開始疼痛減輕，15例病患在手術後1週各癥狀均明顯減輕，所有病患于2週內眼部疼痛、畏光以及流淚等癥狀均解除。病患角膜麵平整、光滑，結膜充血情況得以減輕，且角膜逐漸恢複透明。2年之內堅持隨訪，均無複髮及其他明顯併髮癥髮生。病患手術前後視力情況對比，手術後病患視力為手動及眼前指數的病患所佔比例分彆為0％、14．29％，顯著低于手術前的47．62％、35．71％。且視力為0．01～0．02及0．03～0．04的病患所佔比例分彆為59．52％、26．19％，顯著高于手術前的16．67％、0％。差異均有統計學意義（均P＜0．05）。結論：CICC治療BK，療效顯著，可有效清除角膜大泡病變，解除病患疼痛，併能夠恢複病患視力，無併髮癥髮生，安全性高，具有積極意義，值得推薦。
목적：연구탐토시행각막층간분리청괄술（ Corneal interlameller clean curettage ，CICC）치료대포성각막병변（ Bullous keratopathy ，BK）적림상효과。방법：선취아원종2011년4월～2012년5월피학인위BK병환42례，균유각막상피불동정도수종，차실거광택，유1개혹다개대수포륭기，직경범위약위1～3 mm，부분수포파렬후，용형광소염색정양성。대기여이각막층간분리청괄술치료，관찰기료효이급술후병발증정황，대수술전후병환시력정황기록병진행대비。결과：관찰술후료효급병발증정황，9례병환우수술후2천개시동통감경，15례병환재수술후1주각증상균명현감경，소유병환우2주내안부동통、외광이급류루등증상균해제。병환각막면평정、광활，결막충혈정황득이감경，차각막축점회복투명。2년지내견지수방，균무복발급기타명현병발증발생。병환수술전후시력정황대비，수술후병환시력위수동급안전지수적병환소점비례분별위0％、14．29％，현저저우수술전적47．62％、35．71％。차시력위0．01～0．02급0．03～0．04적병환소점비례분별위59．52％、26．19％，현저고우수술전적16．67％、0％。차이균유통계학의의（균P＜0．05）。결론：CICC치료BK，료효현저，가유효청제각막대포병변，해제병환동통，병능구회복병환시력，무병발증발생，안전성고，구유적겁의의，치득추천。
Objective:To study clinical effect of discussion of corneal interlameller clean curettage ( CICC) in the treatment of bullous keratopathy ( BK) .Methods:Our hospital chose from April 2012 to May 2013 of BK patients , 42 cases had varying degrees of corneal epi-thelial edema, and loss of luster, there were one or more large blisters uplift, diameter range of about after 1 ~3mm, part broken blis-ters, positive staining with fluorescein .It's been clear separation between the layers of the cornea curettage treatment to evaluate efficacy and postoperative complications , visual acuity before and after the surgery the patient was recorded and compared .Results:Observed post-operative effects and complications , 9 cases of patients at the beginning of pain relief 2d after surgery,15 cases of patients one week after surgery's all symptoms were significantly reduced in all patients within 2 weeks of eye pain ,fear light and tearing and other symptoms were released .Patients with corneal surface smooth, conjunctival hyperemia alleviated the situation , and the gradual recovery of corneal trans-parency .Adhere to follow-up within two years , no recurrence and other complications occurred .Visual contrast to the situation before and after surgery for patients , with visual acuity of patients after surgery's proportion of manual and front indices were 0%, 14.29%, 47. 62%, which was significantly lower than before surgery of 35.71%.And visual acuity was 0.01 to 0.02 and 0.03 to 0.04's proportion of patients were 59 .52%, 26 .19%, significantly higher than 16 .67%before surgery ,0%.Differences were statistically significant ( P <0.05).Conclusion:CICC in the treatment of BK, has a significant effect, can effectively remove corneal lesions cannon , relieve pain pa-tients, and be able to restore vision in patients with no complications , which is safe,has a positive meaning.It is recommended .
