中华放射肿瘤学杂志
中華放射腫瘤學雜誌
중화방사종류학잡지
CHINESE JOURNAL OF RADIATION ONCOLOGY
2008年
6期
460-463
,共4页
周立庆%戴建荣%胡逸民%李晔雄%王绿化
週立慶%戴建榮%鬍逸民%李曄雄%王綠化
주립경%대건영%호일민%리엽웅%왕녹화
三维适形放射疗法%简化调强放射疗法%调强放射疗法%剂量验证
三維適形放射療法%簡化調彊放射療法%調彊放射療法%劑量驗證
삼유괄형방사요법%간화조강방사요법%조강방사요법%제량험증
Three dimensional conformal radiotherapy%Simplified intensity modulation radiotherapy%Intensity modulation radiotherapy%Dose verification
目的 探讨简化调强放疗(sIMRT)的剂量验证方法是否可采用与三维适形放疗(3DCRT)照射技术相同的剂量验证方法.方法 从接受sIMRT的1988例患者中随机抽取12例,用Pinnacle计划系统对每个患者分别做3DCRT、slMRT、IMRT治疗计划,用MapCHECK Model 1175 2D半导体剂最仪,在医科达Precise直线加速器上作剂量验证测量.结果 slMRT剂昔偏筹为2%(2mm)、3%(3 mm)的总平均通过率分别为90.5%、94.8%,比3DCRT的92.4%和95.8%分别低1.9%(t=2.19,P=0.040)和似乎低1.0%,但后者差异无统计学意义(t=1.52,P=0.144);剂量偏差为4%(4 mm)的通过率为98.2%,比3DCRT的98.4%似乎低了0.2%,但差异也无统计学意义(t=0.50,P=0.623).而sIMRT剂量偏差为2%(2 mm)、3%(3 mm)、4%(4 mm)的通过率与IMRT的88.4%、93.3%、96.7%相比分别提高了2.1%(t=2.17,P=0.041)、1.5%(t=2.62,P=0.016)、1.5%(t=3.68,P=0.001).结论 sIMRT技术可简化IMRT治疗前剂最验证,在slMRT技术试用期应对每例sIMRT计划进行类似IMRT的剂最学验证方法,以后町采用与3DCRT技术相同或相近的剂昔验证方法.
目的 探討簡化調彊放療(sIMRT)的劑量驗證方法是否可採用與三維適形放療(3DCRT)照射技術相同的劑量驗證方法.方法 從接受sIMRT的1988例患者中隨機抽取12例,用Pinnacle計劃繫統對每箇患者分彆做3DCRT、slMRT、IMRT治療計劃,用MapCHECK Model 1175 2D半導體劑最儀,在醫科達Precise直線加速器上作劑量驗證測量.結果 slMRT劑昔偏籌為2%(2mm)、3%(3 mm)的總平均通過率分彆為90.5%、94.8%,比3DCRT的92.4%和95.8%分彆低1.9%(t=2.19,P=0.040)和似乎低1.0%,但後者差異無統計學意義(t=1.52,P=0.144);劑量偏差為4%(4 mm)的通過率為98.2%,比3DCRT的98.4%似乎低瞭0.2%,但差異也無統計學意義(t=0.50,P=0.623).而sIMRT劑量偏差為2%(2 mm)、3%(3 mm)、4%(4 mm)的通過率與IMRT的88.4%、93.3%、96.7%相比分彆提高瞭2.1%(t=2.17,P=0.041)、1.5%(t=2.62,P=0.016)、1.5%(t=3.68,P=0.001).結論 sIMRT技術可簡化IMRT治療前劑最驗證,在slMRT技術試用期應對每例sIMRT計劃進行類似IMRT的劑最學驗證方法,以後町採用與3DCRT技術相同或相近的劑昔驗證方法.
목적 탐토간화조강방료(sIMRT)적제량험증방법시부가채용여삼유괄형방료(3DCRT)조사기술상동적제량험증방법.방법 종접수sIMRT적1988례환자중수궤추취12례,용Pinnacle계화계통대매개환자분별주3DCRT、slMRT、IMRT치료계화,용MapCHECK Model 1175 2D반도체제최의,재의과체Precise직선가속기상작제량험증측량.결과 slMRT제석편주위2%(2mm)、3%(3 mm)적총평균통과솔분별위90.5%、94.8%,비3DCRT적92.4%화95.8%분별저1.9%(t=2.19,P=0.040)화사호저1.0%,단후자차이무통계학의의(t=1.52,P=0.144);제량편차위4%(4 mm)적통과솔위98.2%,비3DCRT적98.4%사호저료0.2%,단차이야무통계학의의(t=0.50,P=0.623).이sIMRT제량편차위2%(2 mm)、3%(3 mm)、4%(4 mm)적통과솔여IMRT적88.4%、93.3%、96.7%상비분별제고료2.1%(t=2.17,P=0.041)、1.5%(t=2.62,P=0.016)、1.5%(t=3.68,P=0.001).결론 sIMRT기술가간화IMRT치료전제최험증,재slMRT기술시용기응대매례sIMRT계화진행유사IMRT적제최학험증방법,이후정채용여3DCRT기술상동혹상근적제석험증방법.
Objective To study if the dose verification technique for three dimensional conformal radiation therapy ( 3 DCRT) can be applied for simplified intensity modulation radiation therapy ( sIM RT). Methods From 1988 patients treated by sIMRT in our department,12 were chosen randomly for the study. For each case,3 differert plans of 3DCRT,sIMRT,and IMRT were worked out with Pinnacle TPS,and the dose verification for each plan was carried out with Elekta Precise LA by using 2D diode-matrix of MapCHECK Model 1175. Results For slMRT,the overall average percentages of pass points for DD(DTA) 2% (2 mm) ,3% (3 mm)and 4% (4 mm) were 90.5% ,94.8% and 98.2% reapectively,which were slightly worse when comparing with those of 3DCRT with deterioration of 1.9% (t=2.19,P=0.040) ,1.0% (t= 1.52,P=0.144) and 0.2% (t=0.05,P=0.623), but slightly better comparing with those of IMRT with increment of 2.1% (t=2.17,P=0.041) ,1.5% (t=2.62,P=0.016) and 1.5% (t=3.68,P=0.001) for 2% (2 mm) ,3% (3 mm) and 4% (4 mm) ,respectively. Conclusions The sIMRT technique simplifies the complicated dose verification procedure of I MRT. When the sIMRT technique is formally used, the procedure of dose distribution verification for 3DCRT can be used directly for slMRT.
