CAJ | 학술논문

目的探讨三维超声-CT图像融合技术评估肝癌消融安全边界的准确性.方法建立并制作肝癌消融安全边界的大体模型,然后分为消融达到安全边界组和未达安全边界组.利用三维超声-CT图像融合判断消融灶有无达到安全边界,未达安全边界的位置,测量未达安全边界的最大厚度,并将结果与大体标本对比.结果模型的超声、CT图像和大体外观及稳定性符合实验要求.三维超声-CT图像融合判定未达安全边界的敏感性、特异性及准确性分别为93.8％、85.7％及91.3％,提示未达安全边界的象限与大体标本均一致.三维超声-CT图像融合与大体标本测量的未达安全边界最大厚度分别为(3.5±2.0)mm和(3.2±2.0)mm,两者间差异无统计学意义.结论体外实验证明三维超声-CT图像融合技术评价肝癌安全边界具有较高的准确性.
목적 탐토삼유초성-CT도상융합기술평고간암소융안전변계적준학성.방법 건립병제작간암소융안전변계적대체모형,연후분위소융체도안전변계조화미체안전변계조.이용삼유초성-CT도상융합판단소융조유무체도안전변계,미체안전변계적위치,측량미체안전변계적최대후도,병장결과여대체표본대비.결과 모형적초성、CT도상화대체외관급은정성부합실험요구.삼유초성-CT도상융합판정미체안전변계적민감성、특이성급준학성분별위93.8％、85.7％급91.3％,제시미체안전변계적상한여대체표본균일치.삼유초성-CT도상융합여대체표본측량적미체안전변계최대후도분별위(3.5±2.0)mm화(3.2±2.0)mm,량자간차이무통계학의의.결론 체외실험증명삼유초성-CT도상융합기술평개간암안전변계구유교고적준학성.
Objective To design and construct a hepatocellular carcinoma(HCC) phantom,and assess the accuracy of three dimensional ultrasound (3DUS)-CT image fusion in evaluating ablative margin (AM).Methods The phantom was constructed by carrageenan gel and additives.A sphere-shaped HCC model surrounded by a 5 mm layer of AM model was embedded into a cylindrical-shaped ground substance model to form the phantom.After radiofrequency ablation (RFA),HCC model in the phantom was ablated into ablative lesion model.The ultrasound and CT image,macroscopic appearance and stability of the phantom were observed.Twenty-four phantoms were made and ablated into different ablative lesion models in which AM was achieved or not achieved.Outline the HCC and 5mm AM in the 3DCT image and fuse 3DCT image with the 3DUS image of the ablative lesion model to see whether the ablative area could cover the AM,as well as in which quadrant complete ablation of the AM had not been achieved and the maximal thickness of the unachieved AM.The result of the 3DUS-CT image fusion was compared with gross specimen.Results The ultrasound and CT image,macroscopic appearance and stability of the phantom met the demand of this study.The sensitivity,specificity and accuracy of 3DUS-CT image fusion were 93.8％,85.7％ and 91.3％respectively.The quadrant in which complete ablation of AM was not achieved matched with gross specimen.The maximal thickness of the unachieved AM measured by 3DUS-CT image fusion and gross specimen were (3.5 ± 2.0) mm and (3.2 ± 2.0) mm respectively,and no statistic difference was found between the two results.Conclusions The phantom made of carrageenan gel and additives was suitable for the evaluation of AM.3DUS-CT image fusion evaluation of AM was accurate.