CAJ | 학술논문

目的探讨急性蛛网膜下腔出血(SAH)患者脑动静脉循环时间(CCT)与病情和预后的关系.方法 60例发病3 d内的SAH患者行脑数字减影血管造影(DSA)检查并测定其CCT,以病情的轻重、转归和存活患者的生存质量分组,观察CCT与它们的关系.结果 38例GCS 13～15分患者CCT为(13.45 ±1.89)s,22例GCS 3～12分患者CCT为(16.79 ±2.07)s,,2组差异有统计学意义(t=3.76,P=0.001).29例Hunt-Hess分级1～2级患者CCT为(13.06 ±1.83)s,31例Hunt-Hess分级3～5级患者CCT为(15.89±2.06)s,2组差异有统计学意义(t=3.39,P=0.003).17例迟发性缺血损害组患者CCT为(16.84±1.91)s,43例非迟发性缺血损害组患者CCT为(12.94±1.67)s,2组比较差异有统计学意义(t=2.23,P=0.025).46例GOS评分4～5分患者CCT为(13.07±1.89)s,14例GOS评分1～3分患者CCT为(17.11±1.71)s,2组比较差异有统计学意义(t=3.27,P=0.008).结论 SAH患者早期CCT可以反映病情的严重程度,与预后有关.
목적 탐토급성주망막하강출혈(SAH)환자뇌동정맥순배시간(CCT)여병정화예후적관계.방법 60례발병3 d내적SAH환자행뇌수자감영혈관조영(DSA)검사병측정기CCT,이병정적경중、전귀화존활환자적생존질량분조,관찰CCT여타문적관계.결과 38례GCS 13～15분환자CCT위(13.45 ±1.89)s,22례GCS 3～12분환자CCT위(16.79 ±2.07)s,,2조차이유통계학의의(t=3.76,P=0.001).29례Hunt-Hess분급1～2급환자CCT위(13.06 ±1.83)s,31례Hunt-Hess분급3～5급환자CCT위(15.89±2.06)s,2조차이유통계학의의(t=3.39,P=0.003).17례지발성결혈손해조환자CCT위(16.84±1.91)s,43례비지발성결혈손해조환자CCT위(12.94±1.67)s,2조비교차이유통계학의의(t=2.23,P=0.025).46례GOS평분4～5분환자CCT위(13.07±1.89)s,14례GOS평분1～3분환자CCT위(17.11±1.71)s,2조비교차이유통계학의의(t=3.27,P=0.008).결론 SAH환자조기CCT가이반영병정적엄중정도,여예후유관.
Objective To investigate the relationship between the cerebral circulation time and disease condition and prognosis in patients with acute subarachnoid hemorrhage. Methods DSA were performed to determine the cerebral circulation time (CCT) in 60 patients who had subarachnoid hemorrhage (SAH) within 3 days. The patients were divided into different groups according to the severity of the disease condition,patients with CSC score as 13-15 were assigned as group Ⅰ ,whose CCT was (13.45 ± 1. 89) s. Twenty two patients with GSC score as 3-12 were assigned as group Ⅱ ,whose CCT was (16.79 ± 2. 07) s. There were significant difference between the CCT of the two groups (t =3. 76,P = 0. 001). (2)Twenty-nine patients with Hunt-Hess grade as 1-2 were assigned as group 1,whose CCT was (13.06 ± 1. 83) s. Thirty one patients with Hunt-Hess grade as 3-5 were assigned as group 2, whose CCT was (15. 89 ± 2.06) s. There were significant difference between the CCT of the two groups (t = 3. 39, P =0. 003). (3) Seventeen patients with delayed ischemic damage were assigned as group A, whose CCT was (16. 84 ±1.91) s. Forty three patients without delayed ischemic damage were assigned as group B, whose CCT was (12.94 ± 1. 67) s. There were significant difference between the CCT of the two groups (t = 2. 23, P =0.025). (4)Forty-six patients with GOS score as 4-5 were assigned as group a,whose CCT was (13.07 ±1. 89)s. Fourteen patients with GSC score as 1-3 were assigned as group b,whose CCT was (17.11 ± 1. 71)s. There were significant difference between the CCT of the two groups (t = 3. 27, P = 0.008). Conclusion CCT may reflect the severity of the SAH in early onset patients and has prognostic value.