中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2011年
4期
260-263
,共4页
曲安奈德%前房注射%老年性白内障%手术%炎症反应
麯安奈德%前房註射%老年性白內障%手術%炎癥反應
곡안내덕%전방주사%노년성백내장%수술%염증반응
Triamcinolone acetonide%Intracameral%Senile cataract%Surgery%Inflammation
目的 探讨老年性白内障术中前房注射不同浓度曲安奈德(TA)控制术后炎症反应的效果.方法 老年性白内障手术60例(60 眼),随机分为3组,每组20眼.A组在手术结束时向前房内注射TA 0.1 mg/0.2 mL;B组前房内注射TA 0.2 mg/0.2 mL.A、B组术后滴妥布霉素滴眼液,4次/d,连用1周.C组(对照组),手术结束时前房内注射灌注液,术后滴妥布霉素地塞米松滴眼液,4次/d,连用3周.术后随访1个月.术后6～8 h测量眼压,术后1 d.2 d,7 d、15 d、30 d观察前房细胞及房水闪光,测量眼压、检查视力及眼底.结果 术后1 d、2 d、7 d、15 d、30 d,3个组之间前房细胞比较(P=1),房水闪光比较(P=1),差异均无统计学意义,术后6～8 h,1 d、2 d、7 d、15 d、30 d,3个组之间眼压比较,差异无统计学意义.结论 老年性白内障术中前房注射0.1 mg/0.2 mL或0.2 mg/0.2 mL的曲安奈德都能有效地控制术后的炎症反应,无明显不良影响,重要的是术后可以不用糖皮质激素,从而减少了频繁滴眼的麻烦,也避免了由其引起的并发症.
目的 探討老年性白內障術中前房註射不同濃度麯安奈德(TA)控製術後炎癥反應的效果.方法 老年性白內障手術60例(60 眼),隨機分為3組,每組20眼.A組在手術結束時嚮前房內註射TA 0.1 mg/0.2 mL;B組前房內註射TA 0.2 mg/0.2 mL.A、B組術後滴妥佈黴素滴眼液,4次/d,連用1週.C組(對照組),手術結束時前房內註射灌註液,術後滴妥佈黴素地塞米鬆滴眼液,4次/d,連用3週.術後隨訪1箇月.術後6～8 h測量眼壓,術後1 d.2 d,7 d、15 d、30 d觀察前房細胞及房水閃光,測量眼壓、檢查視力及眼底.結果 術後1 d、2 d、7 d、15 d、30 d,3箇組之間前房細胞比較(P=1),房水閃光比較(P=1),差異均無統計學意義,術後6～8 h,1 d、2 d、7 d、15 d、30 d,3箇組之間眼壓比較,差異無統計學意義.結論 老年性白內障術中前房註射0.1 mg/0.2 mL或0.2 mg/0.2 mL的麯安奈德都能有效地控製術後的炎癥反應,無明顯不良影響,重要的是術後可以不用糖皮質激素,從而減少瞭頻繁滴眼的痳煩,也避免瞭由其引起的併髮癥.
목적 탐토노년성백내장술중전방주사불동농도곡안내덕(TA)공제술후염증반응적효과.방법 노년성백내장수술60례(60 안),수궤분위3조,매조20안.A조재수술결속시향전방내주사TA 0.1 mg/0.2 mL;B조전방내주사TA 0.2 mg/0.2 mL.A、B조술후적타포매소적안액,4차/d,련용1주.C조(대조조),수술결속시전방내주사관주액,술후적타포매소지새미송적안액,4차/d,련용3주.술후수방1개월.술후6～8 h측량안압,술후1 d.2 d,7 d、15 d、30 d관찰전방세포급방수섬광,측량안압、검사시력급안저.결과 술후1 d、2 d、7 d、15 d、30 d,3개조지간전방세포비교(P=1),방수섬광비교(P=1),차이균무통계학의의,술후6～8 h,1 d、2 d、7 d、15 d、30 d,3개조지간안압비교,차이무통계학의의.결론 노년성백내장술중전방주사0.1 mg/0.2 mL혹0.2 mg/0.2 mL적곡안내덕도능유효지공제술후적염증반응,무명현불량영향,중요적시술후가이불용당피질격소,종이감소료빈번적안적마번,야피면료유기인기적병발증.
Objective To explore the efficacy and safety of intracameral triamcinolone acetonide (TA)for controlling ocular inflammation in patients after cataract surgery.Methods Sixty patients(60eyes)with senile cataract in our hospital were divided into group A,B and C before surgery randomly.Group A(20 eyes)and group B(20 eyes)were injected 0.1 mg/0.2 mL and 0.2 mg/0.2 mL TA into the anterior chamber respectively during surgery.Next.group A and B were administeraned tobramyein 0.3%eyedrops 4 times per day for one week.Group C Were administeraned tobramycin 0.3%and dexamethasone 0.1%eyedrops 4 times per day for three weeks with no TA.Anterior chamber cells.anterior chamber flare were assessed at postoperative day 1,2,7,15 and 30 by slit-lamp biomicroscopy.Visual acuity,intraocular pressure,and fundus were valued at postoperative 6-8 h,day 1,2,7,15 and 30.Results There were no statistically significant differences in the amount of anterior chamber cells,flare and IOP in the three groups at all timepoint assessed.(P＞0.05).Conclusion Intraeameral TA 0.1 mg/0.2 ml,0.2 mg/0.2 ml can effectively control postoperative inflammation after age-related cataract surgery,and can decrease the dosage and duration of topical prednisolone acetate.
