中药新药与临床药理
中藥新藥與臨床藥理
중약신약여림상약리
TRADITIONAL CHINESE DRUG RESEARCH&CLINICAL PHARMACOLOGY
2009年
4期
344-347
,共4页
崔红花%高幼衡%蔡鸿飞%魏志雄%梁盛林%何巧君
崔紅花%高幼衡%蔡鴻飛%魏誌雄%樑盛林%何巧君
최홍화%고유형%채홍비%위지웅%량성림%하교군
川佛手%芸香科%化学成分
川彿手%蕓香科%化學成分
천불수%예향과%화학성분
Citrus medica L. var. sarcodactylis Swingle from Sichuan Province%Rutaceae%Chemical constituents
目的 研究芸香科柑橘属植物川佛手Citrusmedica var.sarcodactylis的化学成分,为该药材的开发利用和质量评价提供依据.方法 采用各种色谱技术进行分离纯化,通过理化常数测定和波谱分析进行.结果 从川佛手中又分离得到7个化合物,其结构鉴定为:5-羟基-7-甲氧基-8-异戊烯基香豆素(sibiricol,Ⅵ)、6-羟基-7-甲氧基香豆素(7-methylesculetin,Ⅶ)、佛手柑内酯(bergapten,Ⅵ)、Sigmasteryl acetate(Ⅸ)、5-甲氧基-糠醛(5-methoxyfurfural,Ⅹ)、柠檬苦素(limonin,Ⅺ)、胡萝卜苷(daucosterol,Ⅻ).结论 化合物Ⅵ、Ⅶ、Ⅸ为从芸香科植物中首次分离得到.
目的 研究蕓香科柑橘屬植物川彿手Citrusmedica var.sarcodactylis的化學成分,為該藥材的開髮利用和質量評價提供依據.方法 採用各種色譜技術進行分離純化,通過理化常數測定和波譜分析進行.結果 從川彿手中又分離得到7箇化閤物,其結構鑒定為:5-羥基-7-甲氧基-8-異戊烯基香豆素(sibiricol,Ⅵ)、6-羥基-7-甲氧基香豆素(7-methylesculetin,Ⅶ)、彿手柑內酯(bergapten,Ⅵ)、Sigmasteryl acetate(Ⅸ)、5-甲氧基-糠醛(5-methoxyfurfural,Ⅹ)、檸檬苦素(limonin,Ⅺ)、鬍蘿蔔苷(daucosterol,Ⅻ).結論 化閤物Ⅵ、Ⅶ、Ⅸ為從蕓香科植物中首次分離得到.
목적 연구예향과감귤속식물천불수Citrusmedica var.sarcodactylis적화학성분,위해약재적개발이용화질량평개제공의거.방법 채용각충색보기술진행분리순화,통과이화상수측정화파보분석진행.결과 종천불수중우분리득도7개화합물,기결구감정위:5-간기-7-갑양기-8-이무희기향두소(sibiricol,Ⅵ)、6-간기-7-갑양기향두소(7-methylesculetin,Ⅶ)、불수감내지(bergapten,Ⅵ)、Sigmasteryl acetate(Ⅸ)、5-갑양기-강철(5-methoxyfurfural,Ⅹ)、저몽고소(limonin,Ⅺ)、호라복감(daucosterol,Ⅻ).결론 화합물Ⅵ、Ⅶ、Ⅸ위종예향과식물중수차분리득도.
Objective To investigate the chemical constituents of Citrus medica var. sareodactylis from Sichuan province, and to provide evidence for the development and utilization and quality evaluation of the medicinal material.Methods Various chromatographic techniques were used to purify the components of this herb. Compounds were identi-fied by their physical characteristics and spectral feature. Results Seven compounds were isolated from Citrus medica var. sarcodactylis, and they were identified as sibiricol (Ⅵ), 7-methylesculetin (Ⅶ), bergapten (Ⅷ), sigmasteryl acetate(Ⅸ), 5-methoxyfurfural(Ⅹ), limonin(Ⅺ), daucosterol (Ⅻ). Conclusion Compound Ⅵ, Ⅶ and Ⅸ are isolated from plants of Rutaceae for the first time.
