CAJ | 학술논문

减肥有助于治疗肥胖伴发2型糖尿病,但目前尚无有效的药物治疗肥胖症.减肥外科手术能达到明显有效且持续的减重效果.约30%接受减肥手术的患者伴发2型糖尿病,减肥手术后多数患者的2型糖尿病得到缓解(胃肠Bypass手术的有效率为84%～98%,限制食物摄人型手术的有效率为55%～84%).本综述重点讨论各种类型的减肥手术治疗2型糖尿病的疗效及其可能的发生机制.
감비유조우치료비반반발2형당뇨병,단목전상무유효적약물치료비반증.감비외과수술능체도명현유효차지속적감중효과.약30%접수감비수술적환자반발2형당뇨병,감비수술후다수환자적2형당뇨병득도완해(위장Bypass수술적유효솔위84%～98%,한제식물섭인형수술적유효솔위55%～84%).본종술중점토론각충류형적감비수술치료2형당뇨병적료효급기가능적발생궤제.
Although weight loss is beneficial for obese patients with diabetes, current medical treatment for obesity is difficult. Bariatric surgery leads to substantial and durable weight reduction.Nearly 30% of patients who undergo bariatric surgery have type 2 diabetes.For many of them, diabetes resolves following bariatric surgery (83% to 93% for bypass procedures and 55% to 84% for restrictive procedures).This review discusses the effects of various bariatric procedures on type 2 diabetes mellitus and their possible mechanisms.