CAJ | 학술논문

家族性电紊乱性心脏病未植入心律转复除颤器患者的长期随访研究
가족성전문란성심장병미식입심률전복제전기환자적장기수방연구
Long-term follow-up of patients with familial electric disorder cardiomyopathy without ICD implantation

万方数据

中华心律失常学杂志中華心律失常學雜誌 중화심률실상학잡지
CHINESE JOURNAL OF CARDIAC ARRHYTHMIAS
2008年 2期 107-109 ,共3页

刘金秋%刘莹%高连君%夏云龙%董颖雪%李真%杨东辉%王莹琦%洪丽%潘晓杰%张树龙%杨延宗

류금추%류형%고련군%하운룡%동영설%리진%양동휘%왕형기%홍려%반효걸%장수룡%양연종

长QT综合征%Brugada综合征%心脏骤停%随访長QT綜閤徵%Brugada綜閤徵%心髒驟停%隨訪
장QT종합정%Brugada종합정%심장취정%수방
Long QT syndrome%Brugada syndrome%Cardiac arrest%Follow-up

目的研究家族性电紊乱性心脏病高危患者,未植入心律转复除颤器(ICD)的长期预后.方法 13例患者中11例长QT综合征(LQTS)、2例Brugada综合征,均有心脏性晕厥.男性4例,女性9例,平均年龄(44±19)岁.6例(46%)因心跳骤停住院治疗.4例LQTS植入起搏器,平均随访(7±4)年.结果 11例(85%)患者仍然发作晕厥,1例心脏骤停首次入院,5例(39%)心脏骤停再入院,2例LQTS死亡,其中1例(0.8%)猝死.结论 LQTS和Brugada综合征患者一旦出现晕厥,以后会反复发作,如果没有条件接受ICD治疗,其他的药物治疗、医生的密切监控随访、指导患者避免触发因素和针对家属的心肺复苏训练同样非常重要.
목적 연구가족성전문란성심장병고위환자,미식입심률전복제전기(ICD)적장기예후.방법 13례환자중11례장QT종합정(LQTS)、2례Brugada종합정,균유심장성훈궐.남성4례,녀성9례,평균년령(44±19)세.6례(46%)인심도취정주원치료.4례LQTS식입기박기,평균수방(7±4)년.결과 11례(85%)환자잉연발작훈궐,1례심장취정수차입원,5례(39%)심장취정재입원,2례LQTS사망,기중1례(0.8%)졸사.결론 LQTS화Brugada종합정환자일단출현훈궐,이후회반복발작,여과몰유조건접수ICD치료,기타적약물치료、의생적밀절감공수방、지도환자피면촉발인소화침대가속적심폐복소훈련동양비상중요.
Objective To evaluate the long-term prophylactics of high-risk patients with hereditary arrhythmia at absence of implantable cardioverter defibrillator(ICD) treatment. Methods Eleven cases of congenital tong QT syndrome (LQTS) and 2 cases Brugada syndrome were enrolled,4 male,9 female with average age (44 ± 19)years. Routine clinical investigation and electrocardiography(ECG) were delivered. All patients experienced syncope or aborted cardiac arrest. Six cases (46%) were hospitalized due to cardiac arrest. Four patients with LQTS were implanted pacemakers. Patients were educated to avoid trigger factors of cardiac events and families were trained with cardiac pulmonary resuscitation. Results LQTS patients still experienced syncope or cardiac arrest after propranolol and pacemaker therapy but attacks occurred less than before. One LQTS had her first cardiac arrest. Five LQTS(39%) had cardiac arrest again during follow-up. Two LQTS cases died. One (0. 8%)died of sudden cardiac attack. The other died of cerebral hemorrhage. Both Brugada syndrome patients had cardiac arrest and survived again. One case experienced 5 times cardiac arrest and was saved by his wife's cardiac pulmonary resuscitations. Conclusiou LQTS and Brugada syndrome patients are in high risk for sudden cardiac death. Β-blocker and pacemaker may be effective to improve symptoms. With or without ICD implantation, patients should be educated to avoid trigger factors of cardiac evens and was families should be trained with cardiac pulmonary resuscitation.