CAJ | 학술논문

生物体内分子网络巾信息的传输、储存、放大、整合等大量仟务可以看成是一种生物分子计算过程.文中提出了一种活体分子计算模型,借助RNA干扰技术和乳糖操纵子调控模型,在细胞内构建了一个基因网络,用于求解图的最小支配集.该模型展示了利用牛物体自身的信息处理能力进行计算的能力,在生物体内建立具有一定智能的分子机器,这将在计算科学、生物学、医学上有着深远的应用前景.
생물체내분자망락건신식적전수、저존、방대、정합등대량천무가이간성시일충생물분자계산과정.문중제출료일충활체분자계산모형,차조RNA간우기술화유당조종자조공모형,재세포내구건료일개기인망락,용우구해도적최소지배집.해모형전시료이용우물체자신적신식처리능력진행계산적능력,재생물체내건립구유일정지능적분자궤기,저장재계산과학、생물학、의학상유착심원적응용전경.
Biomolecular computing models in vivo are an emerging computing model inspired from the biological phenomena that the biochemical molecular in living perform computation,communications,and signal processing collaboratively. In this paper,a biomolecular computing model in vivo for minimum dominating set problem is presented,a synthetic gene network is constructed by RNAi and lactose operon in living cell.This model explores further the ability to solve hard problems based on organism processing signal,and try to construct an intelligent molecule machine in cell.It may be widely and further used in computing science,biology,and medicine.