CAJ | 학술논문

目的:探讨胃原发性恶性淋巴瘤黏膜活检病例的临床病理诊断特点.方法:内窥镜胃黏膜活检标本和切除标本经常规石蜡包埋切片、染色和免疫组化染色后光镜下观察.结果:31例活检组织中均呈现不同程度的异型淋巴细胞弥漫浸润,腺体数量减少或完全消失;12例出现淋巴上皮病变,7例出现可疑淋巴上皮病变;13例伴有炎症渗出坏死;8例组织挤压损伤.结论:充分、准确的活检对胃淋巴瘤的确诊具有重要意义;异型淋巴细胞弥漫浸润是活检诊断的主要特征,活检组织中可能不出现淋巴上皮病变;免疫组化染色和分子生物学技术可以提高诊断的准确率;内镜医师和病理医师间的合作是提高诊断率的关键.
목적:탐토위원발성악성림파류점막활검병례적림상병리진단특점.방법:내규경위점막활검표본화절제표본경상규석사포매절편、염색화면역조화염색후광경하관찰.결과:31례활검조직중균정현불동정도적이형림파세포미만침윤,선체수량감소혹완전소실;12례출현림파상피병변,7례출현가의림파상피병변;13례반유염증삼출배사;8례조직제압손상.결론:충분、준학적활검대위림파류적학진구유중요의의;이형림파세포미만침윤시활검진단적주요특정,활검조직중가능불출현림파상피병변;면역조화염색화분자생물학기술가이제고진단적준학솔;내경의사화병리의사간적합작시제고진단솔적관건.
Objective:To investigate the pathological characteristics of primary gastric lymphoma in endoscopic biopsied speciments.Methods:All the tissue samples were 10% formalin-fixed,paraffin-embedded,stained and tested with hematoxylin-eosin and SP immunohistochemistry.Results:There were variable atypia,diffuse lymphoid cell infiltration with decrease or disappearance of the gland in the biopsied sample;The lymphoepithelial lesions were seen in 12 cases and suspect lymphoepithelial lesions in 7 cases;There were inflammatory necrosis and pressing tissues injury in 13 cases. Conclusions:The main diagnostic characteristics of gastric lymphoma are variable atypia,diffuse lymphoid cell infiltration in the biopsied tissues;Lymphoepithelial lesions are not always observed,but other changes are often seen in the biopsied samples.