CAJ | 학술논문

白介素17是由Th17细胞分泌的炎症细胞因子,在机体炎症及免疫性疾病中发挥重要作用.皮肤自身免疫性疾病的发病机制尚不清楚.IL-17的炎性和免疫性双重特征,有望在皮肤自身免疫性疾病的研究中取得突破.进一步研究IL-17在皮肤自身免疫性疾病中的作用,探讨其发病机制,可有效寻找新的药物作用靶点和新的治疗方法.
백개소17시유Th17세포분비적염증세포인자,재궤체염증급면역성질병중발휘중요작용.피부자신면역성질병적발병궤제상불청초.IL-17적염성화면역성쌍중특정,유망재피부자신면역성질병적연구중취득돌파.진일보연구IL-17재피부자신면역성질병중적작용,탐토기발병궤제,가유효심조신적약물작용파점화신적치료방법.
The nature of cutaneous autoimmune diseases is still unclear, and at present no specific or effective drug has been found for their treatment. Intedeukin-17 (IL-17) belongs to IL-17 pro-inflammatory cytokine family and is secrete, d by Th17 cells. It plays an important role in inflammatory and autoimmune diseases and is expected to bring a breakthrough in the research of skin autoimmune diseases. Further studies on the role of IL-17 in autoimmune diseases will favor the understanding about their pathogenesis, as well as the search for new treatment targets and approaches to these diseases.