目的 了解肝移植受体的健康相关生存质量(HRQOL)及参加体育锻炼的情况,分析体育锻炼对HRQOL的影响.方法 按照每周是否进行1次有氧体育活动,每次持续30 min以上的标准,将2004年1月至2010年12月第四军医大学西京医院器官移植中心进行术后随访的110例肝移植受体分为锻炼组26例和非锻炼组84例.以简明健康调查量表(SF-36)为主要研究工具,对110例肝移植受体者进行HRQOL调查,同时收集肝移植受体的一般资料、并发症情况和参加体育锻炼情况.结果 肝移植受体中锻炼组患者的高血压(11％)、关节炎(2％)和骨质疏松(3％)发生率明显低于非锻炼组(56％,25％,29％),两组比较,差异有统计学意义(x2分别为4.95,5.22,5.29；P ＜0.05).锻炼组BMI指数为(22.9±4.6),非锻炼组为(27.4±6.8),两组比较,差异有统计学意义(t=3.16,P=0.002)；乙型肝炎、糖尿病、恶性肿瘤的发生率比较,差异无统计学意义(P＞0.05)；与非锻炼组相比,锻炼组的总评分值、生理功能健康总评分(PCS)、PF、RP、BP、GH、VT分值均有不同程度升高[(65.89±24.57)比(49.92±20.59),(69.24±29.64)比(40.71±20.96),(81.35±32.53)比(34.56±17.40),(75.12±39.27)比( 55.85±29.26),( 60.26±27.68)比(27.23±16.69),(61.29±25.32)比(46.02±22.58),(54.84±20.45)比(44.25±25.83)],两组比较,差异有统计学差异(x2分别为3.31,2.13,9.57,4.57,7.61,2.94,1.92,P＜0.05)；RE、SF和MCS分值比较,差异无统计学意义(x2分别为1.39,0.45,1.17;P ＞0.05).多因素回归分析表明,体育锻炼、BMI指数及患关节炎和骨质疏松是肝移植受体生理健康和HRQOL的主要影响因素.结论 体育锻炼对于肝移植受体保持生理健康,改善生存质量,具有积极意义.
目的 瞭解肝移植受體的健康相關生存質量(HRQOL)及參加體育鍛煉的情況,分析體育鍛煉對HRQOL的影響.方法 按照每週是否進行1次有氧體育活動,每次持續30 min以上的標準,將2004年1月至2010年12月第四軍醫大學西京醫院器官移植中心進行術後隨訪的110例肝移植受體分為鍛煉組26例和非鍛煉組84例.以簡明健康調查量錶(SF-36)為主要研究工具,對110例肝移植受體者進行HRQOL調查,同時收集肝移植受體的一般資料、併髮癥情況和參加體育鍛煉情況.結果 肝移植受體中鍛煉組患者的高血壓(11％)、關節炎(2％)和骨質疏鬆(3％)髮生率明顯低于非鍛煉組(56％,25％,29％),兩組比較,差異有統計學意義(x2分彆為4.95,5.22,5.29；P ＜0.05).鍛煉組BMI指數為(22.9±4.6),非鍛煉組為(27.4±6.8),兩組比較,差異有統計學意義(t=3.16,P=0.002)；乙型肝炎、糖尿病、噁性腫瘤的髮生率比較,差異無統計學意義(P＞0.05)；與非鍛煉組相比,鍛煉組的總評分值、生理功能健康總評分(PCS)、PF、RP、BP、GH、VT分值均有不同程度升高[(65.89±24.57)比(49.92±20.59),(69.24±29.64)比(40.71±20.96),(81.35±32.53)比(34.56±17.40),(75.12±39.27)比( 55.85±29.26),( 60.26±27.68)比(27.23±16.69),(61.29±25.32)比(46.02±22.58),(54.84±20.45)比(44.25±25.83)],兩組比較,差異有統計學差異(x2分彆為3.31,2.13,9.57,4.57,7.61,2.94,1.92,P＜0.05)；RE、SF和MCS分值比較,差異無統計學意義(x2分彆為1.39,0.45,1.17;P ＞0.05).多因素迴歸分析錶明,體育鍛煉、BMI指數及患關節炎和骨質疏鬆是肝移植受體生理健康和HRQOL的主要影響因素.結論 體育鍛煉對于肝移植受體保持生理健康,改善生存質量,具有積極意義.
목적 료해간이식수체적건강상관생존질량(HRQOL)급삼가체육단련적정황,분석체육단련대HRQOL적영향.방법 안조매주시부진행1차유양체육활동,매차지속30 min이상적표준,장2004년1월지2010년12월제사군의대학서경의원기관이식중심진행술후수방적110례간이식수체분위단련조26례화비단련조84례.이간명건강조사량표(SF-36)위주요연구공구,대110례간이식수체자진행HRQOL조사,동시수집간이식수체적일반자료、병발증정황화삼가체육단련정황.결과 간이식수체중단련조환자적고혈압(11％)、관절염(2％)화골질소송(3％)발생솔명현저우비단련조(56％,25％,29％),량조비교,차이유통계학의의(x2분별위4.95,5.22,5.29；P ＜0.05).단련조BMI지수위(22.9±4.6),비단련조위(27.4±6.8),량조비교,차이유통계학의의(t=3.16,P=0.002)；을형간염、당뇨병、악성종류적발생솔비교,차이무통계학의의(P＞0.05)；여비단련조상비,단련조적총평분치、생리공능건강총평분(PCS)、PF、RP、BP、GH、VT분치균유불동정도승고[(65.89±24.57)비(49.92±20.59),(69.24±29.64)비(40.71±20.96),(81.35±32.53)비(34.56±17.40),(75.12±39.27)비( 55.85±29.26),( 60.26±27.68)비(27.23±16.69),(61.29±25.32)비(46.02±22.58),(54.84±20.45)비(44.25±25.83)],량조비교,차이유통계학차이(x2분별위3.31,2.13,9.57,4.57,7.61,2.94,1.92,P＜0.05)；RE、SF화MCS분치비교,차이무통계학의의(x2분별위1.39,0.45,1.17;P ＞0.05).다인소회귀분석표명,체육단련、BMI지수급환관절염화골질소송시간이식수체생리건강화HRQOL적주요영향인소.결론 체육단련대우간이식수체보지생리건강,개선생존질량,구유적겁의의.
Objective To investigate the effects of physical activty on the health-related quality of life (HRQOL) in liver transplant recipients.Methods According with the standard of physical activity participation in cardiovascular exercise one or more times per week for 30 min,totally 110 liver tranplantation recipients from Xi Jing Hospital,Affiliated to the Fourth Military Medical University between January 2004 and December 2011 were divided into active group ( 26 cases ) and inactive group ( 84 cases).And the patients were investigated with the medical outcomes study short form 36 (SF-36).The general datas,coexisting medical conditions and participation in regular physical activity were collected additionally.Results Significant differences between active and inactive subjects in the scores for the following scales were found:total score of SF-36 [ (65.89 ±24.57) vs (49.92 ±20.59) ],PCS[ (69.24 ±29.64) vs (40.71 ±20.96)],PF[(81.35 ±32.53) vs (34.56 ±17.40) ],RP[(75.12 ±39.27) vs (55.85 ±29.26) ],BP[ (60.26 ±27.68) vs (27.23 ±16.69)],GH[(61.29±25.32) vs (46.02±22.58)],VT[(54.84±20.45) vs (44.25±25.83)] (x2 =3.31,2.13,9.57,4.57,7.61,2.94,1.92,respectively; P ＜ 0.05 ).But the score of RE,SF and MCS has no difference between active and inactive group( x2 =1.39,0.47,1.71,respectively; P ＞ 0.05).Compared with active group,the morbidity of hypertension,arthritis and osteopotosis and the value of BMI index of inactive group were higher.Multiple regression analysis indicated the related main factors of the recipients' physical health and HRQOL were physical activity,time posttransplantation,BMI and the morbidity of arthritis and osteopotosis.Conclusions Physical activity is very important to maintain physical health and improve HRQOL for liver transplant recipients.
