国际外科学杂志
國際外科學雜誌
국제외과학잡지
INTERNATIONAL JOURNAL OF SURGERY
2011年
6期
399-401
,共3页
蛋白质组学%胰腺癌%早期诊断%标志物
蛋白質組學%胰腺癌%早期診斷%標誌物
단백질조학%이선암%조기진단%표지물
Proteomics%Pancreatic cancer%Early diagnosis%Biomarkers
胰腺癌的治疗效果取决于早期发现和有效的治疗方法.目前胰腺癌早期诊断十分困难,以至于胰腺癌的发现常常处于中晚期,治疗效果不理想.近年来蛋白质组学技术的快速发展给胰腺癌的早期发现带来希望,成为后基因时代功能基因组学研究的热点.通过蛋白质组学技术从胰腺癌患者血清、胰液和组织中分离和鉴定出差异性蛋白质,从而为胰腺癌的的发病机制和早期诊断提供理论依据和新思路.
胰腺癌的治療效果取決于早期髮現和有效的治療方法.目前胰腺癌早期診斷十分睏難,以至于胰腺癌的髮現常常處于中晚期,治療效果不理想.近年來蛋白質組學技術的快速髮展給胰腺癌的早期髮現帶來希望,成為後基因時代功能基因組學研究的熱點.通過蛋白質組學技術從胰腺癌患者血清、胰液和組織中分離和鑒定齣差異性蛋白質,從而為胰腺癌的的髮病機製和早期診斷提供理論依據和新思路.
이선암적치료효과취결우조기발현화유효적치료방법.목전이선암조기진단십분곤난,이지우이선암적발현상상처우중만기,치료효과불이상.근년래단백질조학기술적쾌속발전급이선암적조기발현대래희망,성위후기인시대공능기인조학연구적열점.통과단백질조학기술종이선암환자혈청、이액화조직중분리화감정출차이성단백질,종이위이선암적적발병궤제화조기진단제공이론의거화신사로.
Therapeutic effect of pancreatic cancer depends on early detection and effective treatment.The early diagnosis of pancreatic cancer is so difficult that the discovery of pancreatic cancer is often in mid and late stages,so the treatment of meaning is not so satisfying.In recent years the rapid study of proteomics has brought great hope in the early discovery of pancreatic cancer to make it the post-genome era of functional genomics research in hot areas.Separating and identifying the serum、juice and tissue of patients with pancreatic cancer to find out the different proteins between normal and sick individuals can provide theoretical base and new ideas for the pathogenesis and early diagnosis of pancreatic cancer.