CAJ | 학술논문

利用131I清除甲状腺癌术后残留甲状腺组织(清甲)是分化型甲状腺癌(DTC)术后治疗中的重要步骤.清甲效果受诸多因素影响,包括口服131I的剂量、DTC的手术方式、术后甲状腺组织残留量、血清促甲状腺激素(TSH)与甲状腺球蛋白(Tg)水平、有无淋巴结及远处转移、手术距13I治疗时间的长短等.使用较大剂量131I进行清甲、采取甲状腺全切或近全切除术方式、131I治疗前较高水平的TSH,以及术后及时开始131I治疗等有助于提高清甲成功率.131I治疗前患者血清Tg水平偏高或存在转移灶,应适当加大131I治疗剂量.患者性别、年龄、病理类型等对清甲成功与否无明显影响.
이용131I청제갑상선암술후잔류갑상선조직(청갑)시분화형갑상선암(DTC)술후치료중적중요보취.청갑효과수제다인소영향,포괄구복131I적제량、DTC적수술방식、술후갑상선조직잔류량、혈청촉갑상선격소(TSH)여갑상선구단백(Tg)수평、유무림파결급원처전이、수술거13I치료시간적장단등.사용교대제량131I진행청갑、채취갑상선전절혹근전절제술방식、131I치료전교고수평적TSH,이급술후급시개시131I치료등유조우제고청갑성공솔.131I치료전환자혈청Tg수평편고혹존재전이조,응괄당가대131I치료제량.환자성별、년령、병리류형등대청갑성공여부무명현영향.
Radioiodine ablation of thyroid remnants after surgery is an important part of the treatment of differentiated thyroid carcinoma. The effect of ablation therapy is affected by many factors ,such as the administration dose of radioiodine, mode of operation, amount of thyroid remnants, the serum level of thyroidstimulating hormone and thyroglobulin, whether lymph nodes or distant metastasis are existed, the period of time between the ablation treatment and the operation and so on. Relative high dose of radioiodine,total or near-total thyroidectomy, high level of thyroid-stimulating hormone, ablation treatment onset after surgery without delay would contributed to the success of thyroid ablation. If the patient's thyroglobulin levels are high or metastasis foci are existed, the dose of radioiodine should increase to some extent. While patient's gender, age and pathology are unrelated to the treating effect.