CAJ | 학술논문

目的调查北京老年人轻度认知损害(MCD)与年龄、性别、体质指数等的关系.方法应用简易精神状态检查,对北京东直门社区招募的129例老年人进行认知功能评估.结果检出记忆型轻度认知损害(aMCI)37例(28.7%),阿尔茨海默病(AD)36例(27.9%),认知正常者56例(43.4%).aMCI和AD患者年龄高于认知正常者,分别为(67.6±7.5)岁、(66.6±8.2)岁和(62.5±7.9)岁,两两比较差异均有统计学意义(t值分别为2.847、-1.747和-2.429,P>0.05、P<0.01和P<0.01);aMCI和AD患者受教育年限低(P<0.05);aMCI和AD患者的血压较认知正常者高(P<0.05);aMCI体质指数高于其他两组(P<0.05),不同性别老年人aMCI和AD患病率差异无统计学意义(P>0.05);不同月份出生aMCI和AD患病率差异无统计学意义(P>0.05).结论 aMCI患病率与年龄、教育程度、高血压和体质指数等因素有关,与性别、出生月份无关.
목적 조사북경노년인경도인지손해(MCD)여년령、성별、체질지수등적관계.방법 응용간역정신상태검사,대북경동직문사구초모적129례노년인진행인지공능평고.결과 검출기억형경도인지손해(aMCI)37례(28.7%),아이자해묵병(AD)36례(27.9%),인지정상자56례(43.4%).aMCI화AD환자년령고우인지정상자,분별위(67.6±7.5)세、(66.6±8.2)세화(62.5±7.9)세,량량비교차이균유통계학의의(t치분별위2.847、-1.747화-2.429,P>0.05、P<0.01화P<0.01);aMCI화AD환자수교육년한저(P<0.05);aMCI화AD환자적혈압교인지정상자고(P<0.05);aMCI체질지수고우기타량조(P<0.05),불동성별노년인aMCI화AD환병솔차이무통계학의의(P>0.05);불동월빈출생aMCI화AD환병솔차이무통계학의의(P>0.05).결론 aMCI환병솔여년령、교육정도、고혈압화체질지수등인소유관,여성별、출생월빈무관.
Objective To investigate the risk factors for mild cognitive impairment (MCI) in elderly people in Beijing.Methods Using multistage cluster random sampling,129 elderly people aged 60-80 years living around Dongzhimen communities were interviewed by mini-mental state examination (MMSE) and National Institute of Neurological and Communicative Diseases and Stroke/ Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria for screening MCI and Alzheimer's disease (AD).Results Thirty-seven cases (28.7%) had amnestic MCI (aMCI),thirty-six cases (27.9%) had AD,and fifty-six cases (43.4%) were with normal cognitive state (NCS).The age was older in aMCI patients or AD patients than in NCS[(67.6±7.5)y vs.(62.5±7.9)y,(67.6±7.5)y vs.(62.5±7.9)y,both P<0.01],Andthe aMCI or AD patients had low level of education (P<0.05).The blood pressure was higher in the patients suffered from aMCI or AD than in people with NCS more or less (P<0.05).The prevalence of aMCI was related to the body mass index (BMI) (P<0.05),while that of AD had no significant relation with BMI (P>0.05).The prevalence of aMCI or AD was not significantly different between male and female or between different birth months.(all P>0.05).Conclusions The prevalence of aMCI increases with age,lower level of education,higher level of blood pressure and BMI,while it has no significant relations with gender or birth month.