国际免疫学杂志
國際免疫學雜誌
국제면역학잡지
INTERNATIONAL JOURNAL OF IMMUNOLOGY
2012年
3期
242-244
,共3页
IL-6%糖尿病肾病
IL-6%糖尿病腎病
IL-6%당뇨병신병
Interleukin-6%Diabetic nephropathy
目的 探讨血、尿IL-6变化在糖尿病肾病诊断治疗中的意义.方法 将实验对象分为观察组和对照组,观察组52人,对照组40人.根据尿白蛋白排泄率(UAER)将观察组又分为两个小组:分别为微量蛋白尿组DN1(24例)和临床蛋白尿组DN2(28例).对照组选取40名健康成年人.观察各组血、尿IL-6水平.结果 ①观察组病人血、尿IL-6水平高于正常对照组.②观察组中DN2组血、尿IL-6水平比DN1组升高的更明显.结论 糖尿病肾病患者的血、尿IL-6水平高于健康有,IL-6水平在糖尿病肾病的进展中发生变化,血、尿IL-6水平测定对糖尿病肾病的诊断及治疗具有一定意义.
目的 探討血、尿IL-6變化在糖尿病腎病診斷治療中的意義.方法 將實驗對象分為觀察組和對照組,觀察組52人,對照組40人.根據尿白蛋白排洩率(UAER)將觀察組又分為兩箇小組:分彆為微量蛋白尿組DN1(24例)和臨床蛋白尿組DN2(28例).對照組選取40名健康成年人.觀察各組血、尿IL-6水平.結果 ①觀察組病人血、尿IL-6水平高于正常對照組.②觀察組中DN2組血、尿IL-6水平比DN1組升高的更明顯.結論 糖尿病腎病患者的血、尿IL-6水平高于健康有,IL-6水平在糖尿病腎病的進展中髮生變化,血、尿IL-6水平測定對糖尿病腎病的診斷及治療具有一定意義.
목적 탐토혈、뇨IL-6변화재당뇨병신병진단치료중적의의.방법 장실험대상분위관찰조화대조조,관찰조52인,대조조40인.근거뇨백단백배설솔(UAER)장관찰조우분위량개소조:분별위미량단백뇨조DN1(24례)화림상단백뇨조DN2(28례).대조조선취40명건강성년인.관찰각조혈、뇨IL-6수평.결과 ①관찰조병인혈、뇨IL-6수평고우정상대조조.②관찰조중DN2조혈、뇨IL-6수평비DN1조승고적경명현.결론 당뇨병신병환자적혈、뇨IL-6수평고우건강유,IL-6수평재당뇨병신병적진전중발생변화,혈、뇨IL-6수평측정대당뇨병신병적진단급치료구유일정의의.
Objective To determine The clinical significance of interleukin-6 by examining the changes in blood and urine from diabetic nephropathy patients.Methods The subjects were divided into two groups:52 subjects in the observation group and 40 healthy subjects in the control group,Further dividing the subjects in observation group into two separate groups according to their urinary albumin excretion rate (UAER).Twenty-four patients with microalbumin urine were included in DN1 group,28 with clinical protein urine were included in DN2 group.Observations were made ofthe level of IL-6 in blood and urine.Results ①The levels of IL-6 in observation group were higher than those in control group.②The levels of IL-6 in DN2were significantly higher than those in DN1 group.Conclusion The levels of IL-6 in blood and urine from diabetic nephropathy patients are higher than those in healthy people.The level of IL-6 changes in the progression of diabetic nephropathy It has a certain significance to determinate the level of IL-6 changes in blood and urine according to the diagnosis and treatment for diabetic nephropathy patients.
