CAJ | 학술논문

目的将DNA定量分析及常规细胞学与病理组织学诊断结果进行比较研究,评估DNA定量分析对宫颈病变筛查的临床价值,探讨其对细胞学ASCUS进行分流的意义.方法经DNA定量分析及常规细胞学后建议行阴道镜检查并有详细病理报告的共180例患者结果进行详细分析.结果在细胞学和DNA倍体均见异常的180名女性当中.以细胞学为ASC-H作为活检标准诊断CIN I以上的敏感性是65%,而以细胞DNA倍体分析结果可见3个以上异倍体细胞作为活检的标准,其诊断CINI以上的敏感性是94%.ASCUS同时伴有DNA倍体异常的84例患者中,其病理结果为CINI以上者占42%(35/84).结论 DNA定量分析系统与常规细胞学诊断相比,具有更高的敏感性,同时可作为ASCUS分流的方法.
목적 장DNA정량분석급상규세포학여병리조직학진단결과진행비교연구,평고DNA정량분석대궁경병변사사적림상개치,탐토기대세포학ASCUS진행분류적의의.방법 경DNA정량분석급상규세포학후건의행음도경검사병유상세병리보고적공180례환자결과진행상세분석.결과 재세포학화DNA배체균견이상적180명녀성당중.이세포학위ASC-H작위활검표준진단CIN I이상적민감성시65%,이이세포DNA배체분석결과가견3개이상이배체세포작위활검적표준,기진단CINI이상적민감성시94%.ASCUS동시반유DNA배체이상적84례환자중,기병리결과위CINI이상자점42%(35/84).결론 DNA정량분석계통여상규세포학진단상비,구유경고적민감성,동시가작위ASCUS분류적방법.
Objective Compare the value of conventional cytology and DNA image cytometry(DNAICM)with the results of histopathology,evaluate the clinical value in cervical lesions screening,discuss the significance of the shunt by using conventional cytology ASCUS.Methods Choose results of 180 patients who were examed by cytology and image cytomery,in the end,all of these patients were taken by colposcope examination,and analysed these results.Results Among the 180 patients whose conventional cytology and ONA image cytometry were nomal,makeing conventional cytology ASC-H as the standards of biopsies,the sensitivity in diagnosis of CINI and over CINI was 65%.makeing DNA image cytometry which can see heteroploid cell of 3 and more than 3 as the standards of biopsies,the sensitivity in diagnoswas of CINI and over CINI was 94%.Among the patients whose ASCUS with ploidy abnomal,the results of histopathology proved CINI and over CINI is 42% (35/84).Conclusion DNA image cytometry has higher sensitivity than conventional cytology,at the same time,and it is a way as the shunt of ASCUS.