自然科学进展(英文版)
自然科學進展(英文版)
자연과학진전(영문판)
PROGRESS IN NATURAL SCIENCE
2004年
5期
377-387
,共11页
quorum sensing%bacterial communication%N-acyl-homoserine lactone%bacterial biofilms
Bacteria can communicate with each other by means of signal molecules to coordinate the behavior of the entire community,and the mechanism is referred to as quorum sensing (QS).Signal systems enable bacteria to sense the size of their densities by monitoring the concentration of the signal molecules.Among Gram-negative bacteria N-acyl-L-homoserine lactone (acyl-HSL)-dependent quorum sensing systems are particularly widespread.These systems are used to coordinate expression of phenotypes that are fundamental to the interaction of bacteria with each other and with their environment and particularly higher organisms,covering a variety of functions ranging from pathogenic to symbiotic interactions.The detailed knowledge of these bacterial communication systems has opened completely new perspectives for controlling undesired microbial activities.