CAJ | 학술논문

目的观察早期乳腺癌保留乳房术后放射治疗的疗效、乳房美容效果及并发症.方法随访2001年1月至2008年9月治疗的78例早期乳腺癌患者,其中Ⅰ期36例,Ⅱ期42例.术后全乳切线照射50 Gy,瘤床追加电子线照射10 Gy.淋巴结阳性者,患侧锁骨上X线和电子线混合照射50 Gy.结果随访6～98个月,局部复发率4.9%,3年总体生存率96.6%,5年总体生存率92.7%,乳房美容满意率94.9%,治疗后并发症主要有皮肤急性反应及上肢水肿.结论乳房保留手术加术后根治性放射治疗早期乳腺癌可获得满意的生存率及美容效果,提高了患者的存活质量.
목적 관찰조기유선암보류유방술후방사치료적료효、유방미용효과급병발증.방법 수방2001년1월지2008년9월치료적78례조기유선암환자,기중Ⅰ기36례,Ⅱ기42례.술후전유절선조사50 Gy,류상추가전자선조사10 Gy.림파결양성자,환측쇄골상X선화전자선혼합조사50 Gy.결과 수방6～98개월,국부복발솔4.9%,3년총체생존솔96.6%,5년총체생존솔92.7%,유방미용만의솔94.9%,치료후병발증주요유피부급성반응급상지수종.결론 유방보류수술가술후근치성방사치료조기유선암가획득만의적생존솔급미용효과,제고료환자적존활질량.
Objective To observe the oncololigcal and cosmetic outcomes and complication of breastconserving surgery and radiotherapy for early breast cancer. Methods A total of 78 early breast cancer patients, who were treated in the First People's Hospital of Pingdingshan between January 2001 and September 2008, were identified and followed. Among them, 36 were in stage Ⅰ and 42 in stage Ⅱ. Tangential irradiation was used with a dose of 50 Gy. Tumor bed received a boost dose of 10 Gy electron beam. For axillary lymph node-positive patients, ipsilateral supraclavicular field was hybrid irradiated with 50 Gy X and electron beam.Results The total follow-up ranged from 6 to 98 months. Local recurrence was observed among 4.9% of the patients. The 3-year and 5-year overall survival rate were 96.6% and 92.7% ,respectively. The breast cosmetic satisfaction rate was 94.9%. The main complications reported were acute skin reaction and upper limb edema.Conclusion Breast-conserving surgery and post-operative radiotherapy in early breast cancer patients can lead to satisfactory survival rates and cosmetic effects and hence improved life quality.