中华神经科杂志
中華神經科雜誌
중화신경과잡지
Chinese Journal of Neurology
2012年
1期
36-39
,共4页
入睡和睡眠障碍%神经心理学测验%记忆%前瞻性研究
入睡和睡眠障礙%神經心理學測驗%記憶%前瞻性研究
입수화수면장애%신경심이학측험%기억%전첨성연구
Sleep initiation and maintenance disorde%Neuropsychological tests%Memory%Prospective studie
目的 探讨慢性失眠对患者前瞻性记忆的损害情况.初步探讨慢性失眠引起前瞻性记忆损害的可能神经机制.方法 采用前瞻性记忆的神经心理学测试方法,对42例慢性原发性失眠患者及40名正常睡眠者进行基于事件和基于时间的前瞻性记忆测试.结果 与正常睡眠组[(5.58±0.35)分]比较,慢性原发性失眠组[(3.44±0.40)分]患者基于事件的前瞻性记忆差异有统计学意义(t=3.933,P=0.000)；基于事件的前瞻性记忆的回溯成分差异无统计学意义(t=1.308,P =0.195)；基于时间的前瞻性记忆差异无统计学意义(t=0.787,P=0.433)；基于时间的前瞻性记忆的同溯成分差异无统计学意义(Z=-0.776,P=0.437).结论 慢性失眠影响患者基于事件的前瞻性记忆,而基于时间的前瞻性记忆及同溯成分相对正常.
目的 探討慢性失眠對患者前瞻性記憶的損害情況.初步探討慢性失眠引起前瞻性記憶損害的可能神經機製.方法 採用前瞻性記憶的神經心理學測試方法,對42例慢性原髮性失眠患者及40名正常睡眠者進行基于事件和基于時間的前瞻性記憶測試.結果 與正常睡眠組[(5.58±0.35)分]比較,慢性原髮性失眠組[(3.44±0.40)分]患者基于事件的前瞻性記憶差異有統計學意義(t=3.933,P=0.000)；基于事件的前瞻性記憶的迴溯成分差異無統計學意義(t=1.308,P =0.195)；基于時間的前瞻性記憶差異無統計學意義(t=0.787,P=0.433)；基于時間的前瞻性記憶的同溯成分差異無統計學意義(Z=-0.776,P=0.437).結論 慢性失眠影響患者基于事件的前瞻性記憶,而基于時間的前瞻性記憶及同溯成分相對正常.
목적 탐토만성실면대환자전첨성기억적손해정황.초보탐토만성실면인기전첨성기억손해적가능신경궤제.방법 채용전첨성기억적신경심이학측시방법,대42례만성원발성실면환자급40명정상수면자진행기우사건화기우시간적전첨성기억측시.결과 여정상수면조[(5.58±0.35)분]비교,만성원발성실면조[(3.44±0.40)분]환자기우사건적전첨성기억차이유통계학의의(t=3.933,P=0.000)；기우사건적전첨성기억적회소성분차이무통계학의의(t=1.308,P =0.195)；기우시간적전첨성기억차이무통계학의의(t=0.787,P=0.433)；기우시간적전첨성기억적동소성분차이무통계학의의(Z=-0.776,P=0.437).결론 만성실면영향환자기우사건적전첨성기억,이기우시간적전첨성기억급동소성분상대정상.
Objective To explore the characteristics and the pathogenetic mechanism of prospective memory in patients with chronic primary insomnia. Methods Forty-two patients with chronic primary insomnia and forty age,gender,education,and cultural level matched healthy adults were assessed with a battery of neuropsychological tests including event-based prospective memory (EBPM) and time-based prospective memory (TBPM) tasks.Results Compared with the healthy controls ( EBPM: 5.58 ± 0.35 ;TBPM: 4.10 ± 0.32),the patients with chronic primary insomnia had a significant loss in EBPM (3.44 ±0.40,t =3.933,P =0.000),but a insignificant impairment in TBPM (3.76 ± 0.29,t =0.787,P =0.433 ).The retrospective component of event-based prospective memory between the two groups had no significant difference ( t =1.308,P =0.195 ) ,neither did the retrospective component of time-based prospective memory ( Z =- 0.776,P =0.437 ).Conclusion These results suggest that the patients with chronic primary insomnia have impairment in EBPM,but not in TBPM and the retrospective component of prospective memory.
