中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2011年
5期
440-443
,共4页
梁登攀%姚晓光%李南方%张德莲%郭艳英%林丽%周玲%李文昌%严治涛%王红梅%罗文利%常建航
樑登攀%姚曉光%李南方%張德蓮%郭豔英%林麗%週玲%李文昌%嚴治濤%王紅梅%囉文利%常建航
량등반%요효광%리남방%장덕련%곽염영%림려%주령%리문창%엄치도%왕홍매%라문리%상건항
血脂异常%危险因素%哈萨克族
血脂異常%危險因素%哈薩剋族
혈지이상%위험인소%합살극족
Dyslipidemias%Risk factor%Kazak
目的 调查新疆阜康地区哈萨克族30岁以上居民的血脂水平.方法 在新疆阜康地区内采用分层整群随机抽样的方法抽取了991名30岁以上的哈萨克族居民,检测其血浆总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、血糖及胰岛素水平,分析该人群血脂水平、血脂异常率及人群分布特点,并探讨其可能的相关风险因素.结果 新疆阜康地区哈萨克族30岁以上居民血清TC、TG、HDL-C、LDL-C水平分别是(5.05±1.07)、(1.10±0.66)、(1.46±0.38)、(3.06±0.84)mmol/L;男性TC、TG及LDL-C分别为(5.19±1.05)、(1.32±0.80)、(3.30±0.85)mmol/L,均明显高于女性的(4.94±1.07)、(0.94±0.46)、(2.88±0.79)mmol/L(t值分别为3.57、8.63、8.06,P值均＜0.01);男性HDL-C水平明显低于女性[分别为(1.32±0.33)、(1.57±0.38)mmol/L,t=11.48,P＜0.01].血脂异常率为28.3%(280/991);TC、TG、HDL-C以及LDL-C异常率分别为12.6%(125/991)、6.6%(65/991)、11.0%(109/991)和10.1%(100/991);TC、TG以及LDL-C边缘异常患病率分别是27.0%(268/991)、7.6%(75/991)和20.5%(203/991).男性血脂异常率达40.0%(172/430);30～39、40～49、50～59、60岁以上组血脂异常患病率分别为26.2%(78/298)、26.0%(91/350)、31.2%(73/234)和34.9%(38/109)(χ2=3.94,P＜0.05).校正性别和年龄后,TG与腰围、腹围、BMI偏相关系数分别是0.368(P＜0.01)、0.336(P＜0.01)、0.331(P＜0.01);HDL-C与腰围、腹围、BMI的相关系数分别是-0.340(P＜0.01)、-0.339(P＜0.01)、-0.321(P＜0.01).结论 新疆阜康地区哈萨克族居民的血脂处于较高水平,以高TC、高LDL-C为主要特点;该人群中,血脂异常的防治应以男性、血脂边缘异常和60岁以上的人群为重点.
目的 調查新疆阜康地區哈薩剋族30歲以上居民的血脂水平.方法 在新疆阜康地區內採用分層整群隨機抽樣的方法抽取瞭991名30歲以上的哈薩剋族居民,檢測其血漿總膽固醇(TC)、甘油三酯(TG)、高密度脂蛋白膽固醇(HDL-C)、低密度脂蛋白膽固醇(LDL-C)、血糖及胰島素水平,分析該人群血脂水平、血脂異常率及人群分佈特點,併探討其可能的相關風險因素.結果 新疆阜康地區哈薩剋族30歲以上居民血清TC、TG、HDL-C、LDL-C水平分彆是(5.05±1.07)、(1.10±0.66)、(1.46±0.38)、(3.06±0.84)mmol/L;男性TC、TG及LDL-C分彆為(5.19±1.05)、(1.32±0.80)、(3.30±0.85)mmol/L,均明顯高于女性的(4.94±1.07)、(0.94±0.46)、(2.88±0.79)mmol/L(t值分彆為3.57、8.63、8.06,P值均＜0.01);男性HDL-C水平明顯低于女性[分彆為(1.32±0.33)、(1.57±0.38)mmol/L,t=11.48,P＜0.01].血脂異常率為28.3%(280/991);TC、TG、HDL-C以及LDL-C異常率分彆為12.6%(125/991)、6.6%(65/991)、11.0%(109/991)和10.1%(100/991);TC、TG以及LDL-C邊緣異常患病率分彆是27.0%(268/991)、7.6%(75/991)和20.5%(203/991).男性血脂異常率達40.0%(172/430);30～39、40～49、50～59、60歲以上組血脂異常患病率分彆為26.2%(78/298)、26.0%(91/350)、31.2%(73/234)和34.9%(38/109)(χ2=3.94,P＜0.05).校正性彆和年齡後,TG與腰圍、腹圍、BMI偏相關繫數分彆是0.368(P＜0.01)、0.336(P＜0.01)、0.331(P＜0.01);HDL-C與腰圍、腹圍、BMI的相關繫數分彆是-0.340(P＜0.01)、-0.339(P＜0.01)、-0.321(P＜0.01).結論 新疆阜康地區哈薩剋族居民的血脂處于較高水平,以高TC、高LDL-C為主要特點;該人群中,血脂異常的防治應以男性、血脂邊緣異常和60歲以上的人群為重點.
목적 조사신강부강지구합살극족30세이상거민적혈지수평.방법 재신강부강지구내채용분층정군수궤추양적방법추취료991명30세이상적합살극족거민,검측기혈장총담고순(TC)、감유삼지(TG)、고밀도지단백담고순(HDL-C)、저밀도지단백담고순(LDL-C)、혈당급이도소수평,분석해인군혈지수평、혈지이상솔급인군분포특점,병탐토기가능적상관풍험인소.결과 신강부강지구합살극족30세이상거민혈청TC、TG、HDL-C、LDL-C수평분별시(5.05±1.07)、(1.10±0.66)、(1.46±0.38)、(3.06±0.84)mmol/L;남성TC、TG급LDL-C분별위(5.19±1.05)、(1.32±0.80)、(3.30±0.85)mmol/L,균명현고우녀성적(4.94±1.07)、(0.94±0.46)、(2.88±0.79)mmol/L(t치분별위3.57、8.63、8.06,P치균＜0.01);남성HDL-C수평명현저우녀성[분별위(1.32±0.33)、(1.57±0.38)mmol/L,t=11.48,P＜0.01].혈지이상솔위28.3%(280/991);TC、TG、HDL-C이급LDL-C이상솔분별위12.6%(125/991)、6.6%(65/991)、11.0%(109/991)화10.1%(100/991);TC、TG이급LDL-C변연이상환병솔분별시27.0%(268/991)、7.6%(75/991)화20.5%(203/991).남성혈지이상솔체40.0%(172/430);30～39、40～49、50～59、60세이상조혈지이상환병솔분별위26.2%(78/298)、26.0%(91/350)、31.2%(73/234)화34.9%(38/109)(χ2=3.94,P＜0.05).교정성별화년령후,TG여요위、복위、BMI편상관계수분별시0.368(P＜0.01)、0.336(P＜0.01)、0.331(P＜0.01);HDL-C여요위、복위、BMI적상관계수분별시-0.340(P＜0.01)、-0.339(P＜0.01)、-0.321(P＜0.01).결론 신강부강지구합살극족거민적혈지처우교고수평,이고TC、고LDL-C위주요특점;해인군중,혈지이상적방치응이남성、혈지변연이상화60세이상적인군위중점.
Objectiye To study the lipids level in Kazakan individuals over 30-year-old in Fukang area of Xinjiang. Methods Random cluster multistage sampling method were performed to select the subjects,and 991 individuals aged older than 30 from Fukang of Xinjiang were included. The plasma total cholesterol ( TC ), triglyceride ( TG), high-density lipoprotein cholesterol ( HDL-C), low-density lipoprotein cholesterol ( LDL-C), plasma glucose and insulin were measured. Related adverse cardiovascular risk factors were discussed. Results The mean plasma TC, TG, HDL-C and LDL-C of Kazakan residents over 30-year-old in Fukang of Xinjiang were ( 5.05 ± 1.07 ), ( 1.10 ± 0. 66 ), ( 1.46 ± 0. 38 ) and ( 3.06 ±0. 84)mmol/L,respectively. TC,TG and LDL-C levels in male subjects were higher than those in females (malevs female: TC: (5. 19 ± 1.05) mmol/L vs (4.94 ± 1.07) mmol/L,t=3.57,P＜0. 01;TG:( 1.32 ± 0. 80 ) mmol/L vs ( 0. 94 ± 0. 46 ) mmol/L, t = 8. 63, P ＜ 0. 01; LDL-C: ( 3.30 ± 0. 85 ) mmol/L vs (2. 88 ±0. 79) mmol/L,t =8.06 ,P ＜0. 01 ). While the HDL-C level in male subjects was lower than that of female (male vs female: (1.32 ±0.33) mmol/Lvs (1.57±0.38) mmol/L,t=11.48,P＜0. 01).The prevalence of dyslipidemia was 28. 3% (280/991) in the overall populations. In the overall populations,the prevalence of hypercholesteremia, hypertriglyceridemia, high Iow-density lipoprotein cholesterolemia and low serum high density lipoprotein cholesterolemia were 12.6% ( 125/991 ) , 6. 6% ( 65/991 ) , 11.0%( 109/991 ) and 10. 1% ( 100/991 ) ,respectively. The prevalence of individuals with borderline-high TC ,TG and LDL-C were 27. 0% ( 268/991 ), 7. 6% ( 75/991 ) and 20. 5% ( 203/991 ), respectively. The prevalence of dyslipidemia was 40. 0% (172/430) in male populations. The prevalence of dyslipidemia in group aged 30 - 39,40 - 49,50 - 59,60 and above were 26. 2% ( 78/298 ), 26. 0% ( 91/350 ), 31.2%(73/234) and 34. 9% (38/109), respectively, the trend of prevalence was significant by trend test for groups comparison ( x2 = 3.94, P ＜ 0. 05 ). Adjusting for age and gender, TG was positively correlated with waist circumference,abdominal circumference and BMI, the partial relation coefficients were 0. 368 ( P ＜0. 01 ) ,0. 336( P ＜ 0. 01 ) and 0. 331 ( P ＜ 0. 01 ), respectively, and HDL-C was negatively correlated with waist circumference,abdominal circumference and BMI ,the partial relation coefficients were -0. 340 (P ＜0.01),-0.339 (P＜0.01) and -0.321 (P＜0. 01),respectively. Conclusion The lipid levels of Kazakan residents from Fukang area are high and are characterized by hypercholesteremia and high low-density lipoprotein cholesterolemia, and more attention of the prevention of dyslipidemia in this populations should be paid to males,border-line abnormal and those aged over 60-year old.
