CAJ | 학술논문

目的：用β转化生长因子复合骨形成蛋白(TGF-β/BMP)覆盖狗暴露牙髓，观察TGF-β/BMP的盖髓效果。方法：用活体狗牙作直接盖髓实验，并用组织学方法评价盖髓效果。结果：术后8周，TGF-β/BMP能够诱导牙髓成纤维细胞、内皮细胞增殖并抑制炎症反应，提高牙髓修复能力，有完整的牙本质桥形成。结论：TGF-β/BMP能促进狗牙髓组织修复。
목적：용β전화생장인자복합골형성단백(TGF-β/BMP)복개구폭로아수，관찰TGF-β/BMP적개수효과。방법：용활체구아작직접개수실험，병용조직학방법평개개수효과。결과：술후8주，TGF-β/BMP능구유도아수성섬유세포、내피세포증식병억제염증반응，제고아수수복능력，유완정적아본질교형성。결론：TGF-β/BMP능촉진구아수조직수복。
AIM: Observation of the effects of transforming growth factor- β compounded with bone morphogenetic protein (TGF- β/BMP) on the exposed pulp of dogs. METHODS: The teeth of dogs were used for direct pulp capping experiment and the results were evaluated histopathologically. RESULt: Eight weeks postoperatively TGF- β/BMP was able to induce the proliferations of the pulp cells (fibroblasts)and endothelial cell, inhibit the inflammatory reaction of pulp, and possessed the ability to enhance the pulp repairing, complete dentin bridge was induced. CONCLUSION:TGF- β/BMP can promote the regeneration of dog's pulp tissue.