临床内科杂志
臨床內科雜誌
림상내과잡지
JOURNAL OF CLINICAL INTERNAL MEDICINE
2001年
2期
117-119
,共3页
罗清逢%高孝慈%龙尧%徐军发%郑兴武
囉清逢%高孝慈%龍堯%徐軍髮%鄭興武
라청봉%고효자%룡요%서군발%정흥무
病毒性肝炎%TNF-α%白细胞介素-8%血浆选择素
病毒性肝炎%TNF-α%白細胞介素-8%血漿選擇素
병독성간염%TNF-α%백세포개소-8%혈장선택소
目的 探讨TNF-a、IL-8和P-selectin与慢性肝病的关系。方法 应用双抗体夹心酶联免疫吸附法(ELISA)测定124例慢性肝病患者血清TNF-α、IL-8和P-selectin的水平。结果 慢性肝病患者血清TNF-a、IL-8和P-selectin水平均明显高于对照组(P值均＜0.001，P-selectin组P＜0.01)。结论 TNF-a、IL-8和P-selectin可能参与慢性肝病免疫病理损伤过程。检测血清TNF-α、IL-8和P-selectin水平对判断患者病情和预后有临床实用价值。
目的 探討TNF-a、IL-8和P-selectin與慢性肝病的關繫。方法 應用雙抗體夾心酶聯免疫吸附法(ELISA)測定124例慢性肝病患者血清TNF-α、IL-8和P-selectin的水平。結果 慢性肝病患者血清TNF-a、IL-8和P-selectin水平均明顯高于對照組(P值均＜0.001，P-selectin組P＜0.01)。結論 TNF-a、IL-8和P-selectin可能參與慢性肝病免疫病理損傷過程。檢測血清TNF-α、IL-8和P-selectin水平對判斷患者病情和預後有臨床實用價值。
목적 탐토TNF-a、IL-8화P-selectin여만성간병적관계。방법 응용쌍항체협심매련면역흡부법(ELISA)측정124례만성간병환자혈청TNF-α、IL-8화P-selectin적수평。결과 만성간병환자혈청TNF-a、IL-8화P-selectin수평균명현고우대조조(P치균＜0.001，P-selectin조P＜0.01)。결론 TNF-a、IL-8화P-selectin가능삼여만성간병면역병리손상과정。검측혈청TNF-α、IL-8화P-selectin수평대판단환자병정화예후유림상실용개치。
Objective To investigate the relationship between TNF-a, IL-8, P-selectin and chronic hepatic diseases. Methods The serum TNF-α, IL-8 and plasma selectin levels in 124 patients were measured by ELISA. Results The TNF-α, IL-8 and P-selectin levels are significantly higher than normal controls( P＜0.001,P＜0.01). Conclusion The measurements of serum TNF-α, IL-8 and P-selectin levels have clinical value for judgement patients condition and prognosis.
