中国组织工程研究与临床康复
中國組織工程研究與臨床康複
중국조직공정연구여림상강복
JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH
2010年
16期
2967-2970
,共4页
蒋福刚%熊青荣%王天易%李向成%岑明%夏学巍
蔣福剛%熊青榮%王天易%李嚮成%岑明%夏學巍
장복강%웅청영%왕천역%리향성%잠명%하학외
颅骨%修补材料%钛网%骨水泥%应用
顱骨%脩補材料%鈦網%骨水泥%應用
로골%수보재료%태망%골수니%응용
背景:对颅骨修复材料的分类、性质及其在颅骨修补和塑形中的应用和相关并发症的处理进行归纳总结.方法:第一作者应用计算机检索PubMed数据库(http://www.ncbi.nlm.nih.gov/PubMed),检索关键词"codubix,synmesh,bone cement",限定语言种类为"English";同时检索CNKI数据库(www.cnki.net/index.htm),检索关键词"颅骨修补材料,钛网,骨水泥",限定语言种类为中文.选择文章内容与颅骨修补材料种类、材料学特性、组织相容性及其应用效果相关,同一领域文献则选择近期发表或发表在权威杂志文章.排除重复及较陈旧的文献.共纳入26篇文献.结果:骨水泥组织相容性好但不易被吸收,只应用于部分颅骨的修补.经过对比发现钛因其良好的生物相容性可与颅骨结合,使其应用得到了进一步研究,具备较好的应用前景,但也存在很多不足之处.随着生物工程研究的不断深入,骨组织工程、软骨组织工程等研究的深入将会为颅骨修补材料的开拓提供更广阔的前景.结论:颅骨缺损修补材料有很多种,文内只介绍了其中应用较广泛的一些,结合临床实际工作,修补材料选择时要结合患者的病情、经济条件、当地的设备及技术水平等.若经济条件允许情况下,应首选纯钛网及钛钉,因术中塑形方便,不需处理骨窗缘即可固定,且并发症极少,不影响术后X射线检查,手感良好,均匀美观.自体骨及骨水泥应用时,应注意减少相应的并发症,及时有效的处理,也会获得良好的效果.
揹景:對顱骨脩複材料的分類、性質及其在顱骨脩補和塑形中的應用和相關併髮癥的處理進行歸納總結.方法:第一作者應用計算機檢索PubMed數據庫(http://www.ncbi.nlm.nih.gov/PubMed),檢索關鍵詞"codubix,synmesh,bone cement",限定語言種類為"English";同時檢索CNKI數據庫(www.cnki.net/index.htm),檢索關鍵詞"顱骨脩補材料,鈦網,骨水泥",限定語言種類為中文.選擇文章內容與顱骨脩補材料種類、材料學特性、組織相容性及其應用效果相關,同一領域文獻則選擇近期髮錶或髮錶在權威雜誌文章.排除重複及較陳舊的文獻.共納入26篇文獻.結果:骨水泥組織相容性好但不易被吸收,隻應用于部分顱骨的脩補.經過對比髮現鈦因其良好的生物相容性可與顱骨結閤,使其應用得到瞭進一步研究,具備較好的應用前景,但也存在很多不足之處.隨著生物工程研究的不斷深入,骨組織工程、軟骨組織工程等研究的深入將會為顱骨脩補材料的開拓提供更廣闊的前景.結論:顱骨缺損脩補材料有很多種,文內隻介紹瞭其中應用較廣汎的一些,結閤臨床實際工作,脩補材料選擇時要結閤患者的病情、經濟條件、噹地的設備及技術水平等.若經濟條件允許情況下,應首選純鈦網及鈦釘,因術中塑形方便,不需處理骨窗緣即可固定,且併髮癥極少,不影響術後X射線檢查,手感良好,均勻美觀.自體骨及骨水泥應用時,應註意減少相應的併髮癥,及時有效的處理,也會穫得良好的效果.
배경:대로골수복재료적분류、성질급기재로골수보화소형중적응용화상관병발증적처리진행귀납총결.방법:제일작자응용계산궤검색PubMed수거고(http://www.ncbi.nlm.nih.gov/PubMed),검색관건사"codubix,synmesh,bone cement",한정어언충류위"English";동시검색CNKI수거고(www.cnki.net/index.htm),검색관건사"로골수보재료,태망,골수니",한정어언충류위중문.선택문장내용여로골수보재료충류、재료학특성、조직상용성급기응용효과상관,동일영역문헌칙선택근기발표혹발표재권위잡지문장.배제중복급교진구적문헌.공납입26편문헌.결과:골수니조직상용성호단불역피흡수,지응용우부분로골적수보.경과대비발현태인기량호적생물상용성가여로골결합,사기응용득도료진일보연구,구비교호적응용전경,단야존재흔다불족지처.수착생물공정연구적불단심입,골조직공정、연골조직공정등연구적심입장회위로골수보재료적개탁제공경엄활적전경.결론:로골결손수보재료유흔다충,문내지개소료기중응용교엄범적일사,결합림상실제공작,수보재료선택시요결합환자적병정、경제조건、당지적설비급기술수평등.약경제조건윤허정황하,응수선순태망급태정,인술중소형방편,불수처리골창연즉가고정,차병발증겁소,불영향술후X사선검사,수감량호,균균미관.자체골급골수니응용시,응주의감소상응적병발증,급시유효적처리,야회획득량호적효과.
OBJECTIVE: To summarize the classification, property of skull repair material and the processing of related complications in the application of repairing and remodeling the skull.METHODS: The PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) and CNKI Database (www.cnki.net/index.htm) was searched by the first author using key words of "codubix, synmesh, and bone cement" both in English and Chinese. Articles whose content is related to the types, property, biocompatibility and its application effect of skull repairing materials were selected. In the same field, the articles published by authoritative journals or different races were preferred. The repetitive or obsolete literatures were excluded. After that 26 documents were included in this paper.RESULTS: The bone cement exhibited good histocompatibility, however, it is difficult to be absorbed, thus, it only be used for repairing part of skull defects. The study found that titanium had good biocompatibility and could combine with the skull. Its application had a promising prospect, but there are many inadequacies. With the continuous deepening of bio-engineering, bone tissue engineering, and cartilage tissue engineering, it will provide a broader perspective for the study of skull repair materials.CONCLUSION: There are many kinds of materials for skull repairing, and this paper only introduces some of the widely used ones. Actually, the selection of repairing materials should consider the pathogenetic condition, economic condition, local equipment and technical levels. If possible, titanium mesh and titanium screw are preferred, which is characterized by easy operation, few complication and beautiful appearance: When using autogenous bone or bone cements, if related complications can be reduced and handled effectively, the results will be satisfactory.