CAJ | 학술논문

目的观察用体描仪检测婴幼儿患呼吸道疾病时肺功能的变化情况.方法 2006年1月至2009年1月,北京儿童医院进行肺功能检查的小儿930例,其中患呼吸道疾病的婴幼儿900例,健康婴幼儿30名.检查在药物睡眠状态下进行.采用婴幼儿体描仪,通过描记潮气呼吸流速-容量环,应用被动流速容最技术测量呼吸系统静态顺应性、阻力及体积描记法测定功能残气量等评价肺功能.结果正常婴幼儿潮气呼吸流速一容量环近似圆形或椭圆形.呼吸道疾病的婴幼儿潮气呼吸流速-容量环形状及肺功能参数改变:环变窄、呼气降支凹陷、呼气支或吸气支出现平台.结论患呼吸道疾病的婴幼儿肺功能较正常婴幼儿明显不同,肺功能试验是监测呼吸道疾病病情较理想的方法.
목적 관찰용체묘의검측영유인환호흡도질병시폐공능적변화정황.방법 2006년1월지2009년1월,북경인동의원진행폐공능검사적소인930례,기중환호흡도질병적영유인900례,건강영유인30명.검사재약물수면상태하진행.채용영유인체묘의,통과묘기조기호흡류속-용량배,응용피동류속용최기술측량호흡계통정태순응성、조력급체적묘기법측정공능잔기량등평개폐공능.결과 정상영유인조기호흡류속일용량배근사원형혹타원형.호흡도질병적영유인조기호흡류속-용량배형상급폐공능삼수개변:배변착、호기강지요함、호기지혹흡기지출현평태.결론 환호흡도질병적영유인폐공능교정상영유인명현불동,폐공능시험시감측호흡도질병병정교이상적방법.
Objective To observe the alterations of pulmonary function in infants with respiratory diseases. Methods A total of 900 infants with respiratory diseases were recruited and pulmonary function measured in 30 healthy infants. The tests were performed in the sleeping infants with sedation. Tidal breathing flow-volume (TBFV) loops were recorded when infants were breathing quietly. Passive flow-volume technique was used to obtain static respiratory system compliance and resistance. Functional residual capacity was measured by body plethysmograph. Results The TBFV loop showed proximate round or oval curve in healthy infants. The shape and parameters of TBFV loop had significant differences in infants with respiratory diseases as compared with healthy controls. The TBFV loop displayed a concave expiratory curve and ratio of time to reach tidal peak flow to total expiratory time, the expiratory volume till peak flow divided by the total expiratory volume significantly decreased in infants with small airway obstruction. The expiratory or inspiratory curve showed a plateau and the ratio of mid-expiratory to mid-inspiratory flow was less than 60% or over 150% in infants with upper airway obstruction. The TBFV loop turned narrow and lung volume decreased in infants with restrictive diseases. Conclusion The TBFV loop show proximate round or oval curve in healthy infants. Pulmonary function has significant differences between healthy controls and infants with respiratory diseases. Pulmonary function test is useful in the assessment of respiratory diseases.