中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2009年
12期
1100-1104
,共5页
马雅婷%连士勇%刘志才%程兰平%李变云%全培良%陆建邦%孙喜斌
馬雅婷%連士勇%劉誌纔%程蘭平%李變雲%全培良%陸建邦%孫喜斌
마아정%련사용%류지재%정란평%리변운%전배량%륙건방%손희빈
食管肿瘤%流行病学研究%生命统计
食管腫瘤%流行病學研究%生命統計
식관종류%류행병학연구%생명통계
Esophageal neoplasms%Epidemiologic studies%Vital Statistics
目的 分析1988-2004年河南省林州市食管癌人群的生存水平及变化情况,评价当地食管癌二级预防及临床诊治工作的效果.方法 从林州市肿瘤登记处抽取1988-2004年全部食管癌发病和死亡个案记录,剔除重复及仅有死亡证明书的病例,共获得有效分析的食管癌病例12 160例,男性6914例,女性5246例.计算林州市食管癌患者1992、1997和2002年分性别和分年龄组的生存概率,与食管癌发病死亡数据连接.用现时生存分析方法和队列生存分析方法分别计算食管癌患者1990-1994年、1995-1999年、2000-2004年3个时期的5年观察生存率和相对生存率并进行Z检验.结果 林州市食管癌患者在3个时期的5年相对生存率分别为28.24%、35.24%和40.76%,呈逐年上升趋势(Z值分别为3.94、3.07,P值均<0.05).男性食管癌患者3个时期的5年观察牛存率分别为13.67%、18.08%和22.46%,相对生存率分别为29.94%、36.96%和38.40%.女性食管癌患者3个时期的5年观察生存率分别为15.56%、19.29%和28.01%,相对生存率分别为26.78%、33.12%和43.70%.前两个时期男女食管癌患者的5年观察生存率和相对生存率比较,差异无统计学意义(观察生存率Z值分别为1.48、0.88,P值均>0.05;相对生存率Z值分别为1.27、1.50,P值均>0.05).而在第3个时期女性患者的观察生存率和相对生存率高于男性(观察生存率:Z=3.56,P<0.05;相对生存率:Z=2.09,P<0.05).1995-1999年和2000-2004年两个时期现时生存分析方法计算出的相对生存率(分别为35.24%、40.76%)高于同时期队列生存分析方法的结果(分别为28.77%、33.35%).结论 林州市食管癌患者的生存率在不同时期呈逐渐升高趋势,反映出该地区食管癌的二级预防及临床诊疗水平在不断提高.
目的 分析1988-2004年河南省林州市食管癌人群的生存水平及變化情況,評價噹地食管癌二級預防及臨床診治工作的效果.方法 從林州市腫瘤登記處抽取1988-2004年全部食管癌髮病和死亡箇案記錄,剔除重複及僅有死亡證明書的病例,共穫得有效分析的食管癌病例12 160例,男性6914例,女性5246例.計算林州市食管癌患者1992、1997和2002年分性彆和分年齡組的生存概率,與食管癌髮病死亡數據連接.用現時生存分析方法和隊列生存分析方法分彆計算食管癌患者1990-1994年、1995-1999年、2000-2004年3箇時期的5年觀察生存率和相對生存率併進行Z檢驗.結果 林州市食管癌患者在3箇時期的5年相對生存率分彆為28.24%、35.24%和40.76%,呈逐年上升趨勢(Z值分彆為3.94、3.07,P值均<0.05).男性食管癌患者3箇時期的5年觀察牛存率分彆為13.67%、18.08%和22.46%,相對生存率分彆為29.94%、36.96%和38.40%.女性食管癌患者3箇時期的5年觀察生存率分彆為15.56%、19.29%和28.01%,相對生存率分彆為26.78%、33.12%和43.70%.前兩箇時期男女食管癌患者的5年觀察生存率和相對生存率比較,差異無統計學意義(觀察生存率Z值分彆為1.48、0.88,P值均>0.05;相對生存率Z值分彆為1.27、1.50,P值均>0.05).而在第3箇時期女性患者的觀察生存率和相對生存率高于男性(觀察生存率:Z=3.56,P<0.05;相對生存率:Z=2.09,P<0.05).1995-1999年和2000-2004年兩箇時期現時生存分析方法計算齣的相對生存率(分彆為35.24%、40.76%)高于同時期隊列生存分析方法的結果(分彆為28.77%、33.35%).結論 林州市食管癌患者的生存率在不同時期呈逐漸升高趨勢,反映齣該地區食管癌的二級預防及臨床診療水平在不斷提高.
목적 분석1988-2004년하남성림주시식관암인군적생존수평급변화정황,평개당지식관암이급예방급림상진치공작적효과.방법 종림주시종류등기처추취1988-2004년전부식관암발병화사망개안기록,척제중복급부유사망증명서적병례,공획득유효분석적식관암병례12 160례,남성6914례,녀성5246례.계산림주시식관암환자1992、1997화2002년분성별화분년령조적생존개솔,여식관암발병사망수거련접.용현시생존분석방법화대렬생존분석방법분별계산식관암환자1990-1994년、1995-1999년、2000-2004년3개시기적5년관찰생존솔화상대생존솔병진행Z검험.결과 림주시식관암환자재3개시기적5년상대생존솔분별위28.24%、35.24%화40.76%,정축년상승추세(Z치분별위3.94、3.07,P치균<0.05).남성식관암환자3개시기적5년관찰우존솔분별위13.67%、18.08%화22.46%,상대생존솔분별위29.94%、36.96%화38.40%.녀성식관암환자3개시기적5년관찰생존솔분별위15.56%、19.29%화28.01%,상대생존솔분별위26.78%、33.12%화43.70%.전량개시기남녀식관암환자적5년관찰생존솔화상대생존솔비교,차이무통계학의의(관찰생존솔Z치분별위1.48、0.88,P치균>0.05;상대생존솔Z치분별위1.27、1.50,P치균>0.05).이재제3개시기녀성환자적관찰생존솔화상대생존솔고우남성(관찰생존솔:Z=3.56,P<0.05;상대생존솔:Z=2.09,P<0.05).1995-1999년화2000-2004년량개시기현시생존분석방법계산출적상대생존솔(분별위35.24%、40.76%)고우동시기대렬생존분석방법적결과(분별위28.77%、33.35%).결론 림주시식관암환자적생존솔재불동시기정축점승고추세,반영출해지구식관암적이급예방급림상진료수평재불단제고.
Objective To analyze the survival. level and variation of esophageal. cancer in Linzhou city of Henan province from 1988 to 2004, and evaluate the effects of diagnosis and treatments on esophageal cancer in this area. Methods All incidence and death records for esophageal. cancer during 1988 to 2004 were collected from Linzhou Tumor Registry. Cases with duplicate information or death certificate only were excluded A total. of 12 160 cases of esophageal. cancer were collected,of which,6914 cases were male,and 5246 cases were female. The sex-specific and age-specific probabilities of survival. in 1992,1997 and 2002 were calculated and linked to the data of incidence and death on esophageal. cancer in this area. Five-year observed survival. rate and five-year relative survival. rate during 1990 to 1994,1995 to 1999,2000 to 2004 were calculated respectively using period survival. analysis and cohort survival. analysis and Z test. Results The 5-year relative survival. rates among the three-episode were 28. 24% ,35. 24% and 40. 76% respectively during 1988 to 2004. This showed an increasing trend by periods (Z values were 3. 94 and 3. 07, P < 0.05). The 5-year observed survival. rates in men among the three-episode were 13. 67% , 18. 08% and 22. 46% respectively,the 5-year relative survival. rates were 29. 94% , 36. 96% and 38. 40% . The 5-year observed survival. rates in women among the three-episode were 15. 56% , 19. 29% and 28. 01% respectively, the 5-year relative survival. rates were 26. 78% ,33. 12% and 43. 70%. During the two former periods,there was no significant difference in the 5-year observed survival. rate and relative survival. rate between men and women (Z values of observed survival. rate were 1.48 and 0. 88, P > 0. 05. Z values of relative survival. rate were 1.27 and 1. 50,P>0. 05). In the third period,the 5-year observed survival. rate and relative survival. rate in women was higher than that in men (observed survival. rate Z = 3. 56, P < 0. 05; relative survival. rate Z =2. 09,P<0.05). The relative survival. rate that calculated using period method (respectively 35.24% and 40. 76% ) was higher than that using cohort method ( respectively 28. 77% and 33. 35% ) from 1995 to 1999,and from 2000 to 2004. Conclusion The survival. rate on esophageal. cancer in Linzhou city was increasing in the three different periods. This indicated a rising status in the secondary prevention and clinical diagnosis and treatments on esophageal. cancer.
