中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2012年
3期
56-58
,共3页
肾综合征出血热%急性肾功能衰竭%救肾汤
腎綜閤徵齣血熱%急性腎功能衰竭%救腎湯
신종합정출혈열%급성신공능쇠갈%구신탕
Hemorrhagic fever with renal syndrome%Acute renal failure%Jiushen decoction
目的 探讨自拟救肾汤对肾综合征出血热急性肾功能衰竭的治疗作用.方法 将98例肾综合征出血热急性肾功能衰竭患者随机分为两组,对照组48例采用西医西药治疗,包括支持治疗、利尿等;观察组50例服采用自拟救肾汤(药物组成:生石膏、知母、玄参、生地黄、金银花、连翘、生栀子、黄芩、丹参、川芎、赤芍等)进行治疗,疗程均为1周.观察两组治疗前后尿量、血尿素氮、出血、肾功能、神志等变化.部分患者进行肾活检.结果 治疗后两组症状、体征均有改善,观察组优于对照组(x2=14.16,P<0.05);总有效率观察组(92.0%)优于对照组(60.42%,x2=18.19,P<0.01);观察组组织病理学改变稍优于对照组,但差异无统计学意义.结论 救肾汤有较明显的改善微循环、增加肾血流、改善肾功能等作用.
目的 探討自擬救腎湯對腎綜閤徵齣血熱急性腎功能衰竭的治療作用.方法 將98例腎綜閤徵齣血熱急性腎功能衰竭患者隨機分為兩組,對照組48例採用西醫西藥治療,包括支持治療、利尿等;觀察組50例服採用自擬救腎湯(藥物組成:生石膏、知母、玄參、生地黃、金銀花、連翹、生梔子、黃芩、丹參、川芎、赤芍等)進行治療,療程均為1週.觀察兩組治療前後尿量、血尿素氮、齣血、腎功能、神誌等變化.部分患者進行腎活檢.結果 治療後兩組癥狀、體徵均有改善,觀察組優于對照組(x2=14.16,P<0.05);總有效率觀察組(92.0%)優于對照組(60.42%,x2=18.19,P<0.01);觀察組組織病理學改變稍優于對照組,但差異無統計學意義.結論 救腎湯有較明顯的改善微循環、增加腎血流、改善腎功能等作用.
목적 탐토자의구신탕대신종합정출혈열급성신공능쇠갈적치료작용.방법 장98례신종합정출혈열급성신공능쇠갈환자수궤분위량조,대조조48례채용서의서약치료,포괄지지치료、이뇨등;관찰조50례복채용자의구신탕(약물조성:생석고、지모、현삼、생지황、금은화、련교、생치자、황금、단삼、천궁、적작등)진행치료,료정균위1주.관찰량조치료전후뇨량、혈뇨소담、출혈、신공능、신지등변화.부분환자진행신활검.결과 치료후량조증상、체정균유개선,관찰조우우대조조(x2=14.16,P<0.05);총유효솔관찰조(92.0%)우우대조조(60.42%,x2=18.19,P<0.01);관찰조조직병이학개변초우우대조조,단차이무통계학의의.결론 구신탕유교명현적개선미순배、증가신혈류、개선신공능등작용.
Objective To study the therapeutic effects of self-drafted Jiushen decoction on patients with acute renal failure due to hemorrhagic fever with renal syndrome.Methods Ninty-eight actute renal failure patients were divided into two groups:control group(48 cases) was treated with western medicine,including supportive and diuretic treatment; Treatment group (50 cases) were treated with traditional Chinese medicine of Jiushen decoction ( medicine form:cypsum,anemarrhena asphodel ides,scrophularia ningpoensis hemsl,rehmannia glutinosa,honeysuckle,forsythia suspense,jasmine,scutellaria barcalensis georgi,salvia miltiorrhiza,ligusticum chuanxiong hort,paeonia veitchii).The therapeutic course were 1 week in the two groups.The urine amount and blood plasma carbamide,hemorrhage,kidney function and senses symptoms were observed before and after treatment,and kidney biopsy was performed in part of the patients.Results After treatment,the clinical symptoms and signs were impoved in both groups,but the improvements in observation group were supenor to that in control group (X2 =14.16,P < 0.05).Total effective rate in observation group (92.0% )was higher than that in control group (60.42%,X2 =18.19,P <0.01) ; The histological changes in observation group were better than that in control group,but there was no significant difference.Conclusions The self-drafted Jiushen decoction has good curative effect for microcirculation,it also can improve the kidney function and increase blood replication.