中国组织工程研究与临床康复
中國組織工程研究與臨床康複
중국조직공정연구여림상강복
JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH
2011年
24期
4522-4524
,共3页
诱骗受体1%腰椎%椎间盘%肿瘤坏死因子相关凋亡诱导配体%软组织构建
誘騙受體1%腰椎%椎間盤%腫瘤壞死因子相關凋亡誘導配體%軟組織構建
유편수체1%요추%추간반%종류배사인자상관조망유도배체%연조직구건
背景:诱骗受体1 输肿瘤坏死因子相关凋亡配体受体,其可能作为诱饵受体生理性阻断细胞凋亡过程.目的:观察诱骗受体1 在突出和正常腰椎间盘组织中的表达.方法:2010-01/09 收集退行性椎间盘患者手术切除的突出椎间盘标本20 个及自愿流产的胎儿的正常腰椎间盘标本8 个,免疫组化方法检测诱骗受体1 蛋白在不同椎间盘组织中的分布.结果与结论:突出腰椎间盘组织中诱骗受体1 阳性表达的髓核和纤维环细胞明显多于正常椎间盘,说明突出椎间盘组织中诱骗受体的表达提高.
揹景:誘騙受體1 輸腫瘤壞死因子相關凋亡配體受體,其可能作為誘餌受體生理性阻斷細胞凋亡過程.目的:觀察誘騙受體1 在突齣和正常腰椎間盤組織中的錶達.方法:2010-01/09 收集退行性椎間盤患者手術切除的突齣椎間盤標本20 箇及自願流產的胎兒的正常腰椎間盤標本8 箇,免疫組化方法檢測誘騙受體1 蛋白在不同椎間盤組織中的分佈.結果與結論:突齣腰椎間盤組織中誘騙受體1 暘性錶達的髓覈和纖維環細胞明顯多于正常椎間盤,說明突齣椎間盤組織中誘騙受體的錶達提高.
배경:유편수체1 수종류배사인자상관조망배체수체,기가능작위유이수체생이성조단세포조망과정.목적:관찰유편수체1 재돌출화정상요추간반조직중적표체.방법:2010-01/09 수집퇴행성추간반환자수술절제적돌출추간반표본20 개급자원유산적태인적정상요추간반표본8 개,면역조화방법검측유편수체1 단백재불동추간반조직중적분포.결과여결론:돌출요추간반조직중유편수체1 양성표체적수핵화섬유배세포명현다우정상추간반,설명돌출추간반조직중유편수체적표체제고.
BACKGROUND: Decoy receptor 1 (DcR1), which acts as decoy receptors, is resistant to apoptosis induction by related apoptosis inducing ligand (TRAIL). OBJECTIVE: To investigate the expression of the DcR1 (TRAIL-R3) protein in human herniated and normal lumbar intervertebral discs (IVD). METHODS: The expression and distribution of DcR1 proteins were assessed by using immunohistochemistry in 20 herniated lumbar IVD and 8 normal lumbar IVD tissues samples following discoidectomy from January to September 2010. RESULTS AND CONCLUSION: Percentage of nucleus pulposus and anulus fibrous cells with DCR1 expression was obviously more in the herniated group than in normal IVD group. The current results indicate that the expression of DCR1 rises after herniation.