中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2011年
1期
67-69
,共3页
淋巴细胞性垂体炎%眼部症状%复视%眼睑肿胀
淋巴細胞性垂體炎%眼部癥狀%複視%眼瞼腫脹
림파세포성수체염%안부증상%복시%안검종창
Lymphocytic hypophysitis%Ocular presence%Diplopia%Palpebra swollen
目的 分析有眼部症状的淋巴细胞性垂体炎(LyH)患者的临床特征.方法 回顾性病例系列研究.回顾性分析解放军总医院近10年(1998-2008)内确诊的LyH患者资料,对其年龄、性别、眼部症状及内科症状等特点进行分析.应用独立样本t检验和独立样本校正x2检验分别对年龄和性别进行分析.结果 共有34例LyH患者入选,年龄为13～71岁,平均(41.1±13.9)岁,男10例,女24例.其中有眼部症状者9例(占26.5%),年龄为22～59岁,平均(44.9±12.8)岁,男5例,女4例.LyH患者的眼部症状与体征主要有:复视(6例),眼睑肿胀(4例),视力下降、视野缺损、上睑下垂、眶周疼痛、眼干涩(各2例);其主要眼外症状为:多饮多尿(22例)、头痛(7例)、闭经溢乳(7例)、听觉系统损害(2例).伴有眼部症状的9例LyH患者与总体LyH患者的年龄分布没有明显差异(t=0.961,P=0.704).在性别分布上,总体患者以及无眼部症状患者中均以女性多见(x2=4.03、9.00,P＜0.05),而伴眼部症状者性别差异无统计学意义.结论 LyH患者可伴有多种眼部症状,以复视、眼睑肿胀多见;伴有眼部症状LyH患者与不伴有眼部症状患者的年龄没有差异,但伴有眼部症状患者无性别差异,而不伴有眼部症状及整体LyH患者以女性多见.
目的 分析有眼部癥狀的淋巴細胞性垂體炎(LyH)患者的臨床特徵.方法 迴顧性病例繫列研究.迴顧性分析解放軍總醫院近10年(1998-2008)內確診的LyH患者資料,對其年齡、性彆、眼部癥狀及內科癥狀等特點進行分析.應用獨立樣本t檢驗和獨立樣本校正x2檢驗分彆對年齡和性彆進行分析.結果 共有34例LyH患者入選,年齡為13～71歲,平均(41.1±13.9)歲,男10例,女24例.其中有眼部癥狀者9例(佔26.5%),年齡為22～59歲,平均(44.9±12.8)歲,男5例,女4例.LyH患者的眼部癥狀與體徵主要有:複視(6例),眼瞼腫脹(4例),視力下降、視野缺損、上瞼下垂、眶週疼痛、眼榦澀(各2例);其主要眼外癥狀為:多飲多尿(22例)、頭痛(7例)、閉經溢乳(7例)、聽覺繫統損害(2例).伴有眼部癥狀的9例LyH患者與總體LyH患者的年齡分佈沒有明顯差異(t=0.961,P=0.704).在性彆分佈上,總體患者以及無眼部癥狀患者中均以女性多見(x2=4.03、9.00,P＜0.05),而伴眼部癥狀者性彆差異無統計學意義.結論 LyH患者可伴有多種眼部癥狀,以複視、眼瞼腫脹多見;伴有眼部癥狀LyH患者與不伴有眼部癥狀患者的年齡沒有差異,但伴有眼部癥狀患者無性彆差異,而不伴有眼部癥狀及整體LyH患者以女性多見.
목적 분석유안부증상적림파세포성수체염(LyH)환자적림상특정.방법 회고성병례계렬연구.회고성분석해방군총의원근10년(1998-2008)내학진적LyH환자자료,대기년령、성별、안부증상급내과증상등특점진행분석.응용독립양본t검험화독립양본교정x2검험분별대년령화성별진행분석.결과 공유34례LyH환자입선,년령위13～71세,평균(41.1±13.9)세,남10례,녀24례.기중유안부증상자9례(점26.5%),년령위22～59세,평균(44.9±12.8)세,남5례,녀4례.LyH환자적안부증상여체정주요유:복시(6례),안검종창(4례),시력하강、시야결손、상검하수、광주동통、안간삽(각2례);기주요안외증상위:다음다뇨(22례)、두통(7례)、폐경일유(7례)、은각계통손해(2례).반유안부증상적9례LyH환자여총체LyH환자적년령분포몰유명현차이(t=0.961,P=0.704).재성별분포상,총체환자이급무안부증상환자중균이녀성다견(x2=4.03、9.00,P＜0.05),이반안부증상자성별차이무통계학의의.결론 LyH환자가반유다충안부증상,이복시、안검종창다견;반유안부증상LyH환자여불반유안부증상환자적년령몰유차이,단반유안부증상환자무성별차이,이불반유안부증상급정체LyH환자이녀성다견.
Objective To analyze the clinical ocular features of lymphocytic hypophysitis (LyH). Methods This was a retrospective review of the records of all patients diagnosed with LyH between 1998 and 2008 in our hospital. And their age, gender, ocular clinical and medical symptoms were analyzed. Results There were thirty four consecutive patients with LyH, 13-71 years old [(41.1±13.9)years], 10 males and 24 females. In 34 consecutive patients with LyH, 9 cases (26.5%) had clinical ocular anomalies, 22-59 years old [(44.9±12.8)years], 5 males and 4 females.that included diplopia (6 cases), swollen palpebra (4 cases), and 2 cases each of blurred vision,visual field defect, ptosis, periorbital pain, and dry eye. Extraocular cardinal symptoms included polydipsia and polyuria (22 cases), 7 cases each of headache and amenorrhea, and 2 cases of auditory system damage. The mean age of patients who had LyH accompanied by ocular anomalies was (44.9±12.8) years while the mean age of all patients was (41.1±13.9)years. There was no significant difference in age distribution between the two groups. Among all cases with and without ocular symptoms, there were more females than males (x2=4.03, 9.00, P＜0.05), while there was no significant gender difference in patients with ocular symptoms. Conclusion Some LyH patients have ocular symptom complications. According to our study, the patients who had ocular symptom complications often present with diplopia and/or swollen palpebra. There was no significant age difference between patients with or without ocular symptoms. There was no gender difference in patients with ocular symptoms, but there were more females than males in all patients and in patients without ocular symptoms.
