CAJ | 학술논문

通过建立灌服蜂胶小鼠的渐进负荷游泳训练实验模型,测定了小鼠骨骼肌中超氧化物歧化酶（SOD）的活性和丙二醛（MDA）的含量,以了解蜂胶对运动小鼠骨骼肌自由基代谢的影响.实验结果：灌服蜂胶以后药物组小鼠运动后骨骼肌组织SOD活性显著高于运动组（P〈0.05）;安静组SOD活性显著高于运动组和药物组（P〈0.05）;药物组MDA含量显著低于运动组（P〈0.05）,安静组MDA含量显著低于运动组（P〈0.05）.但安静组和药物组MDA含量并无显著差异（P〉0.05）.结论：蜂胶具有较强的抗自由基氧化损伤的能力和作用.服用蜂胶能有效减轻运动所产生的内源性自由基对小鼠骨骼肌组织的破坏,有利于增强小鼠的运动能力和延缓疲劳的发生.
통과건립관복봉효소서적점진부하유영훈련실험모형,측정료소서골격기중초양화물기화매（SOD）적활성화병이철（MDA）적함량,이료해봉효대운동소서골격기자유기대사적영향.실험결과：관복봉효이후약물조소서운동후골격기조직SOD활성현저고우운동조（P〈0.05）;안정조SOD활성현저고우운동조화약물조（P〈0.05）;약물조MDA함량현저저우운동조（P〈0.05）,안정조MDA함량현저저우운동조（P〈0.05）.단안정조화약물조MDA함량병무현저차이（P〉0.05）.결론：봉효구유교강적항자유기양화손상적능력화작용.복용봉효능유효감경운동소산생적내원성자유기대소서골격기조직적파배,유리우증강소서적운동능력화연완피로적발생.
According to the study, we can know the effect of propolis on the delay of fatigue in training rats. By setting up the model of gradual load training rats, the activity of skeleton muscle mitochondria SOD and the quantity of MDA were measured. The result shows the following： Firstly, rats which are in the propolis group, whose activity of skeleton muscle mitochondria SOD remained at a higher lever than the training group （P〈0.05） after training; Then the activity of skeleton muscle mitochondria SOD in resting group significantly higher than another two group （P〈0.05）. After the gradual load training, the quantity of MDA is higher than the resting group （P〈0.05） ; After the rats took proplis, the quantity of MDA turned lower than that of the training group （P〈0.05）; however, comparing the propolis group with the resting group, there is no significant divergence（P〉0.05）. The result indicate that lipid per-oxidation was increased in or after the gradual load training and propolis produce stronger influence on the anti-oxidation, anti-free-radical, raising exercise endurance and delaying fatigue in rats.