生物技术进展
生物技術進展
생물기술진전
2011年
1期
32-37
,共6页
竞争排斥%益生菌%抗菌素抗性
競爭排斥%益生菌%抗菌素抗性
경쟁배척%익생균%항균소항성
competitive exclusion（CE）%probiotics%antibiotic resistance
竞争排斥益生菌（competitive exclusion product，CE）是1973年由Nurmi和Rantala提出的用于预防和控制刚出壳鸡沙门氏菌感染的复合益生菌产品，后来渐渐扩展到用于其他肠道病原菌的防控。除了控制病原菌定殖外，CE产品也可以促进生长、提高饲料转化率和降低死亡率等。现欧美等国家也开发出20多种CE产品用于养禽和养猪业。关于竞争排斥益生菌的作用机制尚不清楚，但已经提出了一些假说，如竞争粘附位点或营养、刺激局部免疫反应和产生各种各样的抗菌物质等。由于细菌的抗菌素抗性日益严重，CE产品的应用前景将非常广阔。
競爭排斥益生菌（competitive exclusion product，CE）是1973年由Nurmi和Rantala提齣的用于預防和控製剛齣殼鷄沙門氏菌感染的複閤益生菌產品，後來漸漸擴展到用于其他腸道病原菌的防控。除瞭控製病原菌定殖外，CE產品也可以促進生長、提高飼料轉化率和降低死亡率等。現歐美等國傢也開髮齣20多種CE產品用于養禽和養豬業。關于競爭排斥益生菌的作用機製尚不清楚，但已經提齣瞭一些假說，如競爭粘附位點或營養、刺激跼部免疫反應和產生各種各樣的抗菌物質等。由于細菌的抗菌素抗性日益嚴重，CE產品的應用前景將非常廣闊。
경쟁배척익생균（competitive exclusion product，CE）시1973년유Nurmi화Rantala제출적용우예방화공제강출각계사문씨균감염적복합익생균산품，후래점점확전도용우기타장도병원균적방공。제료공제병원균정식외，CE산품야가이촉진생장、제고사료전화솔화강저사망솔등。현구미등국가야개발출20다충CE산품용우양금화양저업。관우경쟁배척익생균적작용궤제상불청초，단이경제출료일사가설，여경쟁점부위점혹영양、자격국부면역반응화산생각충각양적항균물질등。유우세균적항균소항성일익엄중，CE산품적응용전경장비상엄활。
The concept of competitive exclusion （CE） was first proposed by Nurmi and Rantala in 1973. They described that introduction of gut contents originating from that adult birds can protect young birds against Salmonella infection. Then CE products were introduced in preventing and controling other pathogenic bacteria in gut. CE products have other functions, such as promoting growth, improving feed conversion ratio and decreasing mortality rates. Now, more than 20 kinds of CE products were developed and used in livestock and poultry raise in Europe and America. Although, the mechanism of this product is not clear now, some hypothesis have been proposed, such as competition of the attach site or nutrition, stimulation of the immunity response and generation of kinds of anti-bacteria products. Because the popular of antibiotic resistance is becoming more serious, CE products will get a very wide application foreground.
