CAJ | 학술논문

背景:为减少有限元分析的运算量,使之更具有临床实用性,前期试验对赋予材料属性进行了探讨,论证了赋予骨骼10种材料属性可以达到有限元分析的要求,同时发现通过有限元分析的方式,可以实现骨密度值的求解.目的:探讨基于三维重建技术及有限元分析测量骨密度的方法,对骨骼有限元分析的一般过程进行一定规范.方法:选用11侧股骨上段标本,对照组直接测量标本的质量;试验组将11侧标本进行高速CT薄层扫描,在Mimics 10.0中进行三维重建,在Ansys中进行体网格划分,在Mimics中赋予10,100,400种材料属性,输出至Ansys计算骨骼中每一种材料属性的体单元体积,根据CT扫描灰度值与骨密度的经验公式,计算标本质量及密度,进行统计学处理.结果与结论:骨密度单因素方差分析结果显示,对照组与赋予10,100,400种材料属性各试验组差异均无显著性意义(P均＞0.28),试验组各组别之间差异均无显著性意义(P均＞0.8).结果提示,该试验方法可定量测量骨骼质量、密度及骨密质和骨松质的比例,赋予骨骼10种材料属性即可达到测量要求,试验结果可为骨质疏松症的骨密度与有限元分析的统一作初步准备.
배경:위감소유한원분석적운산량,사지경구유림상실용성,전기시험대부여재료속성진행료탐토,론증료부여골격10충재료속성가이체도유한원분석적요구,동시발현통과유한원분석적방식,가이실현골밀도치적구해.목적:탐토기우삼유중건기술급유한원분석측량골밀도적방법,대골격유한원분석적일반과정진행일정규범.방법:선용11측고골상단표본,대조조직접측량표본적질량;시험조장11측표본진행고속CT박층소묘,재Mimics 10.0중진행삼유중건,재Ansys중진행체망격화분,재Mimics중부여10,100,400충재료속성,수출지Ansys계산골격중매일충재료속성적체단원체적,근거CT소묘회도치여골밀도적경험공식,계산표본질량급밀도,진행통계학처리.결과여결론:골밀도단인소방차분석결과현시,대조조여부여10,100,400충재료속성각시험조차이균무현저성의의(P균＞0.28),시험조각조별지간차이균무현저성의의(P균＞0.8).결과제시,해시험방법가정량측량골격질량、밀도급골밀질화골송질적비례,부여골격10충재료속성즉가체도측량요구,시험결과가위골질소송증적골밀도여유한원분석적통일작초보준비.
BACKGROUND:To decrease operation amount of finite element analysis and increase its clinical practice,previous studies explored the material properties and 10 kinds of material attributes were assigned,which met the requirements of finite element analysis.Moreover,it can be used to calculate bone density.OBJECTIVE:To explore a method for measurement of bone density based on three-dimensional reconstruction and finite element analysis.METHODS:A total of 11 specimens of femoral superior segment were selected.The mass of control group was firstly measured.The experimental groups were treated with thin-slice high resolution CT scan and three-dimensional reconstruction in Mimics 10.0,volume meshing in Ansys,assigned with 10,100 and 400 kinds of material attributes Mimics,exported to Ansys to calculat the volumes of the block elements of every types of material attributes.The mass and the density of the specimens was harvested according to the empirical formula concerning the gray value and the bone density.All results were treated with one-way ANOVA.RESULTS AND CONCLUSION:One-way ANOVA showed that there were no significant differences between control group and experimental groups assigned with 10,100 and 400 kinds of material attributes (P＞0.28),and there were no significantly among the experimental groups (P＞0.8).Results show that the method was able to measure the mass and the density of bone quantitatively,as well as the proportion between compact bone and cancellous bone;to assign 10 kinds of material attributes to three-dimensional model of femur could match the needs for measurements.The results can be used as an initial preparation for the unification of bone density and finite element analysis for osteoporosis.