CAJ | 학술논문

目的:分析热致相分离成膜过程的机理、热力学理论基础、动力学机制以及影响因素,以便充分掌握影响孔度大小、分布、形态的因素,使孔度调控范围得以拓宽,使多孔膜的制备能重复可控.方法:从组织工程材料结构特点出发,分析热致相分离聚合物多孔膜的制备方法及该法成膜的热力学理论基础、动力学机制以及影响因素.并分析实验中存在的问题及今后的研究方向.结果:①以热致相分离法可制备聚合物多孔膜.②热致相分离法制备多孔膜是高聚物均相溶液在淬冷条件下发生相分离的过程,它适用于上临界共溶温度型聚合物一稀释剂二元体系.③热致相分离法成膜的过程,可以认为是旋节线机理占主导地位.④热致相分离法制备的微孔材料,其孔隙率、孔径大小、结构形态与聚合物稀释剂的种类、组成配比、聚合物浓度、聚合物分子量等因素密切相关.结论:①可采用热致相分离技术制备多孔膜,通过改变不同的成膜条件可获得一系列不同孔径尺寸和孔径分布的多孔膜材料.②对热致相分离成膜过程中聚合物-溶剂体系的相图测定,不同厚度的多孔膜形貌研究,不同X(聚合物-溶剂相互作用参数)体系所制备的多孔膜形貌等需深人研究.
목적:분석열치상분리성막과정적궤리、열역학이론기출、동역학궤제이급영향인소,이편충분장악영향공도대소、분포、형태적인소,사공도조공범위득이탁관,사다공막적제비능중복가공.방법:종조직공정재료결구특점출발,분석열치상분리취합물다공막적제비방법급해법성막적열역학이론기출、동역학궤제이급영향인소.병분석실험중존재적문제급금후적연구방향.결과:①이열치상분리법가제비취합물다공막.②열치상분리법제비다공막시고취물균상용액재쉬랭조건하발생상분리적과정,타괄용우상림계공용온도형취합물일희석제이원체계.③열치상분리법성막적과정,가이인위시선절선궤리점주도지위.④열치상분리법제비적미공재료,기공극솔、공경대소、결구형태여취합물희석제적충류、조성배비、취합물농도、취합물분자량등인소밀절상관.결론:①가채용열치상분리기술제비다공막,통과개변불동적성막조건가획득일계렬불동공경척촌화공경분포적다공막재료.②대열치상분리성막과정중취합물-용제체계적상도측정,불동후도적다공막형모연구,불동X(취합물-용제상호작용삼수)체계소제비적다공막형모등수심인연구.
AIM:To analyze the mechanism,thermadynamic theoretical basis,dynamic mechanism and influencing factors of thermally induced phase separation (TIPS)in order to completely grasp the factors affecting the size,distribution and form of pores,so that the adjusted range of pore can be widened and the preparation of Porous membrane can be repeated and controlled.METHODS: Considering from the structural characteristics of tissue engineered materials,the methods of preparing porous membrane using TIPS technique,the hermadynamic theoretical basis,dynamic mechanism and influencing factors were analyzed,the problems and investigative directions in the future were also analyzed.TIPS technique is a process of phase separation of polymer homogenous solution under quenching,and it is suitable for diameter and structural form of the micropore materials prepared using TIPS are closely correlated with the kind and dispensing proportion of polymer attrnuant,polymer concentration and polymer molecular mass,etc.conducted,including determination of polymer-solvent system phase diagram,study of form and appearance of porous membrane of different thickness,study of form and appearance of porous membrane prepared with systems of different X,which is the parameter of polymer-solvent interaction.