CAJ | 학술논문

观察大蒜素对不同中医证型不稳定性心绞痛疗效的差异。选择不稳定性心绞痛患者55例随机分为大蒜素组34例，硝酸甘油组21例，治疗10日后，观察疗程前后症状、心电图、血液流变学指标变化。结果示症状有效率和心电图有效率在大蒜素组和硝酸甘油组组间比较无显著差异；对偏寒证不稳定心绞痛的有效率在大蒜素组为100%，硝酸甘油组为75%；大蒜素对偏寒型不稳定心绞痛的有效率为100%，而对偏热者症状有效率为54%（P＜0.001）；大蒜素可明显改善寒证患者的血流变（P<0.05），热证则呈相反变化。提示大蒜素对偏寒证不稳定心绞痛的疗效优于硝酸甘油；大蒜素对偏寒证不稳定心绞痛的疗效优于偏热证不稳定心绞痛，并可明显改善寒证患者的血流变。
관찰대산소대불동중의증형불은정성심교통료효적차이。선택불은정성심교통환자55례수궤분위대산소조34례，초산감유조21례，치료10일후，관찰료정전후증상、심전도、혈액류변학지표변화。결과시증상유효솔화심전도유효솔재대산소조화초산감유조조간비교무현저차이；대편한증불은정심교통적유효솔재대산소조위100%，초산감유조위75%；대산소대편한형불은정심교통적유효솔위100%，이대편열자증상유효솔위54%（P＜0.001）；대산소가명현개선한증환자적혈류변（P<0.05），열증칙정상반변화。제시대산소대편한증불은정심교통적료효우우초산감유；대산소대편한증불은정심교통적료효우우편열증불은정심교통，병가명현개선한증환자적혈류변。
The study was to observe the effects of garlicin on different TCM types of unstable angina pectoris (UAP). 55 Cases of UAP were randomly divided into the garlicin group (consisting of 34 patients) and the nitroglycerin group (consisting of 21 patients), and the changes in symptoms, ECG and blood rheology in patients of both groups were observed before the treatment and 10 days after the treatment. The results showed that there was no significant difference between the effective rates of symptomatic and ECG improvements in both groups; the effective rate of the cold type of UAP of the garlicin group was 100% while that of the nitroglycerin group was 75%. The results also showed that the effective rate of garlicin in treating the febrile type of UAP was 54% (P<0.001); garlicin had markedly effects of improving the state of blood rheology in cases of the cold type of UAP (P<0.05) while it had adverse effects on the state of blood rheology in cases of the febrile type of the disease. From the results it could be seen that the effects of garlicin on the cold type of UAP was better than that of nitroglycerin on the same type of UAP; garlicin had better effects on the cold type of UAP than on the febrile type of the disease, and could also markedly improve the state of blood rheology in patients with the cold type of UAP.