CAJ | 학술논문

目的：通过同时测定牙菌斑、唾液及胃粘膜中幽门螺杆菌(Hp)以了解口腔中Hp的状况及其与胃粘膜病变的关系。方法：采用PCR技术同时测定牙菌斑、唾液及胃粘膜中的幽门螺杆菌。结果：47例胃粘膜Hp阳性的胃窦炎患者中17例(36.2%)牙菌斑中检出Hp；31例(65.9%)唾液标本Hp阳性。而13例胃粘膜Hp阴性者中仍有2例牙菌斑中检出Hp，1例唾液中检出Hp。胃粘膜Hp阳性和阴性者之间牙菌斑及唾液Hp检出率的差异有显著性(P<0.01)。结论：口腔中的Hp可能与胃粘膜中的Hp存在着一定的病因学联系。
목적：통과동시측정아균반、타액급위점막중유문라간균(Hp)이료해구강중Hp적상황급기여위점막병변적관계。방법：채용PCR기술동시측정아균반、타액급위점막중적유문라간균。결과：47례위점막Hp양성적위두염환자중17례(36.2%)아균반중검출Hp；31례(65.9%)타액표본Hp양성。이13례위점막Hp음성자중잉유2례아균반중검출Hp，1례타액중검출Hp。위점막Hp양성화음성자지간아균반급타액Hp검출솔적차이유현저성(P<0.01)。결론：구강중적Hp가능여위점막중적Hp존재착일정적병인학련계。
Objective:To investigate the etiological relation between oral Helicobacter pylori(Hp) and gastric Hp.Methods:Hp in dental plaque,saliva and gastric mucosa from the patients with gastritis was detected with PCR.Results:Hp was found in dental plaque in 17 cases and in saliva in 31 cases out of 47 patients with gastric Hp positive gastritis respectively.Hp was positive in dental plaque in 2 cases and in saliva in 1 case out of 13 gastritis patients with negative gastric Hp.There was a significant difference of Hp positive rate of dental plaque or saliva between patients with positive gastric Hp and those with negative gastric Hp (P<0.01).Conclusion:Oral Hp may be rellated to gastric Hp.