CAJ | 학술논문

目的：了解血吸虫疫区常见消化系恶性肿瘤的发病情况，包括发病率、死亡率、生存率。方法：采用实地回顾性抽样调查的方法对鄱阳湖血吸虫疫区65 680人进行调查统计，分析1988～1996年间5种常见消化系恶性肿瘤的发病率、死亡率及生存率。结果：5种常见恶性肿瘤发病率与死亡率基本呈平行关系，从高到低依次为肝癌(45.85/10万和43.31/10万)、胃癌(28.25/10万和24.53/10万)、食管癌(15.56/10万和13.20/10万)、胰腺癌(524/10万和4.40/10万)和结肠癌(2.54/10万和1.52/10万)。其中肝癌的发病率与死亡率最高，且明显高于上海地区或全国平均水平(P<0.005)。各种恶性肿瘤的男性发病率和死亡率明显高于女性。除结肠癌外，其他4种癌肿大多数生存期短于1年，生存5年以上者极少；平均一年生存率为32.19％，平均两年生存率为15.18％。结论：血吸虫疫区肝癌的发病率和死亡率高于全国水平。
목적：료해혈흡충역구상견소화계악성종류적발병정황，포괄발병솔、사망솔、생존솔。방법：채용실지회고성추양조사적방법대파양호혈흡충역구65 680인진행조사통계，분석1988～1996년간5충상견소화계악성종류적발병솔、사망솔급생존솔。결과：5충상견악성종류발병솔여사망솔기본정평행관계，종고도저의차위간암(45.85/10만화43.31/10만)、위암(28.25/10만화24.53/10만)、식관암(15.56/10만화13.20/10만)、이선암(524/10만화4.40/10만)화결장암(2.54/10만화1.52/10만)。기중간암적발병솔여사망솔최고，차명현고우상해지구혹전국평균수평(P<0.005)。각충악성종류적남성발병솔화사망솔명현고우녀성。제결장암외，기타4충암종대다수생존기단우1년，생존5년이상자겁소；평균일년생존솔위32.19％，평균량년생존솔위15.18％。결론：혈흡충역구간암적발병솔화사망솔고우전국수평。
Objective: To investigate the morbidity, mortality and survival rate of each kind of 5 common cancers in digestive system in the Poyang Lake region endemic for schitosomiasis. Methods: A retrospec tive sampling survey was performed in 65 680 persons in the Poyang Lake region endemic for schitosomia sis, and the morbidity, mortality and survival rate of each kind of 5 common cancers in digestive system from 1988 to 1996 were analyzed respectively. Results: The morbidity (per one hundred thousand) and mortality (per one hundred thousand) of 5 common cancers in descending order were as follows: liver cancer (45.85 and 43. 31), gastric cancer (28. 25 and 24. 53), esophageal cancer (15. 56 and 13. 20), pan creatic cancer (5. 24 and 4. 40) and colonic cancer (2. 54 and 1.52). The morbidity and mortality of liver cancer were the highest of all, and were higher than those in the surveys performed in Shanghai or the whole country (P<0. 005). The morbidity and mortality of each cancer were higher in men than in women. Most of the patients with those cancers (except for colonic cancer) had a survival time less than 1 year, few of them more than 5 years. The mean survival rate of one year was 32. 19%, and the mean sur vival rate of two years was 15. 18%. Conclusions: The morbidity and mortality of liver cancer are higher in the Poyang Lake region endemic for schitosomiasis than in the whole country.