CAJ | 학술논문

目的探讨应用介入方法治疗急性下肢缺血性疾病的临床效果及安全性。方法 21例患者按基础病因不同分为两组，对无患肢慢性缺血史者给予单纯动脉内灌注尿激酶，对存在有患肢慢性缺血史者在给予适当尿激酶30万u后，应用超滑导丝通过闭塞段，顺导丝送入球囊导管行PTA术。结果第1组8例获得成功，1例于术后第3天死于急性左心功能不全；第2组9例获得成功，3例在发病5日后行截肢术。结论 (1) 多种介入方法联合治疗急性下肢缺血临床效果可靠。 (2)基础性病因是决定介入方法选择的首要因素。
목적탐토응용개입방법치료급성하지결혈성질병적림상효과급안전성。방법 21례환자안기출병인불동분위량조，대무환지만성결혈사자급여단순동맥내관주뇨격매，대존재유환지만성결혈사자재급여괄당뇨격매30만u후，응용초활도사통과폐새단，순도사송입구낭도관행PTA술。결과제1조8례획득성공，1례우술후제3천사우급성좌심공능불전；제2조9례획득성공，3례재발병5일후행절지술。결론 (1) 다충개입방법연합치료급성하지결혈림상효과가고。 (2)기출성병인시결정개입방법선택적수요인소。
Objective　To discuss the clinical effect and reliability of interventional method in treating acute lower limb ischemic disease.Methods　21 patients (11 men, 6 women; aged 35-72; average age, 58) were divided into two groups according to difference of basic etiological factor. 9 patients with chronic ischemic history suffering lower limbis in the first group， only urokinase was administrated from artery. 12 patients without chronic ischemic history suffering lower limb was the second group，after delivering a quantity of urokinase (300,000 unit), guide wire was performed across the occlusive segment, then induced Foley's tube for PTA. Results　In the first group, 8 patients succeeded, and one died of acute heart failure three days later; in the second group, 9 patients succeeded, and 3 patients were given amputation 5 days later.Conclusion　(a) The therrapeuti effect of several interventional methods is reliable in treating acute lower limb ischemic disease;(b) Basic etiological factors are a prime element in choosing interventional method.