中华临床医师杂志（电子版）
中華臨床醫師雜誌（電子版）
중화림상의사잡지（전자판）
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2007年
2期
83-85
,共3页
侯建明%林庆明%李建卫%庄维特%陈刚%张超群%林丽香
侯建明%林慶明%李建衛%莊維特%陳剛%張超群%林麗香
후건명%림경명%리건위%장유특%진강%장초군%림려향
血管疾病,外周%糖尿病,2型%脉搏波传播速仪%踝肱指数
血管疾病,外週%糖尿病,2型%脈搏波傳播速儀%踝肱指數
혈관질병,외주%당뇨병,2형%맥박파전파속의%과굉지수
Peripheral vascular disease%Diabetes mellitus,Type 2%Pulse wave velocity%Ankle-brachial index
目的 探讨并发外周动脉疾病(PAD)的糖尿病患者下肢动脉臂踝脉搏波传播速度(baPWV)的改变情况.方法 102例健康对照组和101例2型糖尿病患者(包括PAD患者).用动脉硬化诊断仪测量baPWV和踝肱比值(ABI).结果 无并发PAD的糖尿病患者baPWV高于健康对照组(中位数1 640与1 110 cm/s,P<0.05).并发PAD的糖尿病患者,患肢baPWV低于非患肢baPWV(中位数1 300与1 650 cm/s,P<0.05).对于同年龄组患者(50~70岁),并发PAD的糖尿病患者患肢baPWV(中位数1 300与1 640 cm/s,P<0.05)和ABI(中位数0.8与1.1,P<0.05)均比无并发PAD的糖尿病患者低.并发PAD的糖尿病患者左右baPWV绝对差值均较无并发PAD者大(均P<0.05).并发PAD的糖尿病患者左右baPWV绝对差值与患肢ABI呈负相关(rs=-0.586,P<0.05).结论 糖尿病患者baPWV增加,而并发PAD后患肢baPWV降低,左右baPWV绝对差值可能用于PAD的诊断.
目的 探討併髮外週動脈疾病(PAD)的糖尿病患者下肢動脈臂踝脈搏波傳播速度(baPWV)的改變情況.方法 102例健康對照組和101例2型糖尿病患者(包括PAD患者).用動脈硬化診斷儀測量baPWV和踝肱比值(ABI).結果 無併髮PAD的糖尿病患者baPWV高于健康對照組(中位數1 640與1 110 cm/s,P<0.05).併髮PAD的糖尿病患者,患肢baPWV低于非患肢baPWV(中位數1 300與1 650 cm/s,P<0.05).對于同年齡組患者(50~70歲),併髮PAD的糖尿病患者患肢baPWV(中位數1 300與1 640 cm/s,P<0.05)和ABI(中位數0.8與1.1,P<0.05)均比無併髮PAD的糖尿病患者低.併髮PAD的糖尿病患者左右baPWV絕對差值均較無併髮PAD者大(均P<0.05).併髮PAD的糖尿病患者左右baPWV絕對差值與患肢ABI呈負相關(rs=-0.586,P<0.05).結論 糖尿病患者baPWV增加,而併髮PAD後患肢baPWV降低,左右baPWV絕對差值可能用于PAD的診斷.
목적 탐토병발외주동맥질병(PAD)적당뇨병환자하지동맥비과맥박파전파속도(baPWV)적개변정황.방법 102례건강대조조화101례2형당뇨병환자(포괄PAD환자).용동맥경화진단의측량baPWV화과굉비치(ABI).결과 무병발PAD적당뇨병환자baPWV고우건강대조조(중위수1 640여1 110 cm/s,P<0.05).병발PAD적당뇨병환자,환지baPWV저우비환지baPWV(중위수1 300여1 650 cm/s,P<0.05).대우동년령조환자(50~70세),병발PAD적당뇨병환자환지baPWV(중위수1 300여1 640 cm/s,P<0.05)화ABI(중위수0.8여1.1,P<0.05)균비무병발PAD적당뇨병환자저.병발PAD적당뇨병환자좌우baPWV절대차치균교무병발PAD자대(균P<0.05).병발PAD적당뇨병환자좌우baPWV절대차치여환지ABI정부상관(rs=-0.586,P<0.05).결론 당뇨병환자baPWV증가,이병발PAD후환지baPWV강저,좌우baPWV절대차치가능용우PAD적진단.
Objective The purpose of this study was to examine the alternation in brachial-ankle pulse wave velocity (baPWV) in lower-limb arteries among diabetic patients with peripheral arterial disease (PAD).Methods One hundred and two healthy control subjects and 101 type 2 diabetic patients including those with PAD were admitted.Ankle-brachial index (ABI) and baPWV were also measured with Japanese VS-1000 arteriosclerosis diagnometer.Results Diabetic patients without PAD showed a higher baPWV than healthy control subjects (median 1 640 vs.1 110 cm/s,P<0.05).However,among diabetic patients with PAD,baPWV was lower in the affected legs than in the non-affected legs (median 1 300 vs.1 650 cm/s,P<0.05).The PAD group showed reduction in both baPWV and ABI compared with the non-PAD group in the same age categories (median 1 300 vs.1 640 cm/s;0.8 vs.1.1,P<0.05).The absolute right-left difference in baPWV for diabetic patients with PAD was higher than the non-PAD subjects (P<0.05).In diabetic patients with PAD,the absolute right-left difference in baPWV showed an inverse correlation with ABI (rs=-0.586,P<0.05).Conclusions The baPWV is increased in diabetic patients,whereas it is decreased in the affected legs in diabetic patients with PAD.The absolute right-left difference in baPWV may diagnose PAD.
