中国实验诊断学
中國實驗診斷學
중국실험진단학
CHINESE JOURNAL OF LABORATORY DIAGNOSIS
2009年
7期
935-936
,共2页
姜日花%朱明姬%贾玉玺%蒋忠民
薑日花%硃明姬%賈玉璽%蔣忠民
강일화%주명희%가옥새%장충민
湿疹%特异性IgE%变应原
濕疹%特異性IgE%變應原
습진%특이성IgE%변응원
Eczema%Specific IgE%Allergen
目的 了解慢性湿疹患儿血清特异性IgE和总IgE水平,为预防和治疗该病提供理论依据.方法 采用德国Mediwiss 过敏原体外检测系统,应用免疫印迹定量法对364例慢性湿疹患儿进行血清特异性IgE和总IgE检测.结果 慢性湿疹患儿总 IgE 阳性检出率为48.9%;吸入变应原中户尘螨粉尘螨、蟑螂、矮豚草蒿、狗猫皮屑、霉菌阳性检出率分别为 29.7%,14.3%,13.5%,12.6%,12.1%;食入变应原中蛋白蛋黄、牛奶、鱼虾蟹阳性检出率分别为 18.1%,15.9%,12.6%;1-3岁组食入性变应原的阳性率为高于6-12岁组(P<0.05),而吸入性变应原的阳性率则低于6-12岁组(P<0.05).结论 尘螨、蟑螂、矮豚草蒿、猫毛狗毛皮屑、霉菌、鸡蛋、牛奶、鱼虾蟹是吉林地区小儿慢性湿疹常见的变应原.小于3岁湿疹患儿主要对蛋白蛋黄等食入性变应原过敏,而大于6岁患儿主要对粉尘螨、蟑螂、矮豚草蒿等吸入性变应原过敏.
目的 瞭解慢性濕疹患兒血清特異性IgE和總IgE水平,為預防和治療該病提供理論依據.方法 採用德國Mediwiss 過敏原體外檢測繫統,應用免疫印跡定量法對364例慢性濕疹患兒進行血清特異性IgE和總IgE檢測.結果 慢性濕疹患兒總 IgE 暘性檢齣率為48.9%;吸入變應原中戶塵螨粉塵螨、蟑螂、矮豚草蒿、狗貓皮屑、黴菌暘性檢齣率分彆為 29.7%,14.3%,13.5%,12.6%,12.1%;食入變應原中蛋白蛋黃、牛奶、魚蝦蟹暘性檢齣率分彆為 18.1%,15.9%,12.6%;1-3歲組食入性變應原的暘性率為高于6-12歲組(P<0.05),而吸入性變應原的暘性率則低于6-12歲組(P<0.05).結論 塵螨、蟑螂、矮豚草蒿、貓毛狗毛皮屑、黴菌、鷄蛋、牛奶、魚蝦蟹是吉林地區小兒慢性濕疹常見的變應原.小于3歲濕疹患兒主要對蛋白蛋黃等食入性變應原過敏,而大于6歲患兒主要對粉塵螨、蟑螂、矮豚草蒿等吸入性變應原過敏.
목적 료해만성습진환인혈청특이성IgE화총IgE수평,위예방화치료해병제공이론의거.방법 채용덕국Mediwiss 과민원체외검측계통,응용면역인적정량법대364례만성습진환인진행혈청특이성IgE화총IgE검측.결과 만성습진환인총 IgE 양성검출솔위48.9%;흡입변응원중호진만분진만、장랑、왜돈초호、구묘피설、매균양성검출솔분별위 29.7%,14.3%,13.5%,12.6%,12.1%;식입변응원중단백단황、우내、어하해양성검출솔분별위 18.1%,15.9%,12.6%;1-3세조식입성변응원적양성솔위고우6-12세조(P<0.05),이흡입성변응원적양성솔칙저우6-12세조(P<0.05).결론 진만、장랑、왜돈초호、묘모구모피설、매균、계단、우내、어하해시길임지구소인만성습진상견적변응원.소우3세습진환인주요대단백단황등식입성변응원과민,이대우6세환인주요대분진만、장랑、왜돈초호등흡입성변응원과민.
Objective To study the serum specific IgE (sIgE) and total IgE(tIgE) level in children with chronic eczema and to lie a theoretical foundation for its clinical prevention and treatment.Methods Quantitative immunoblot analysis (Allergy Mediwiss stemystem) was used to examine sIgE and tIgE level in 364 chronic eczema children.All subjects were tested for food-induced and airborne-induced allergens equally.Results The detecting rate of tIgE was 48.9%; while that of dermatophagoides farinae,cockroach,low rag weed,canine and feline scurf,mycetes was 29.7%,14.3%,13.5%,12.6%,12.1%,respectively in airborne-induced group,and of Milk,fish and shrimp,pea crab was 18.1%,15.9%,12.6%,respectively in food-induced group.It showed a significantly higher positive rate of food-induced allergens in toddlers (1-3 years old) than those in school-agers (6-12 years old) (P<0.05),whereas overturned in airborne-induced allergens dramatically(P<0.05).Conclusion Dermatophagoides farinae,cockroach,low rag weed,canine and feline scurf,mycetes,egg white and yolk,milk,fish and shrimp,pea crab were the mainly allergens in children with chronic eczema in Jilin area.Egg white and yolk were dominant food-induced allergens in toddlers,while dermatophagoides farinae,cockroach,low rag weed were leading airborne-induced allergens in school-agers.
