中国有色金属学报(英文版)
中國有色金屬學報(英文版)
중국유색금속학보(영문판)
TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA
2011年
z2期
252-257
,共6页
镁合金%生物降解%生物相容性%细胞毒性
鎂閤金%生物降解%生物相容性%細胞毒性
미합금%생물강해%생물상용성%세포독성
magnesium alloy%biodegradation%biocompatibility%cytotoxicity
研究了挤压态Mg-4.0Zn-0.2Ca合金的体外降解和细胞毒性,通过MTT法用L929细胞检测挤压态Mg-4.0Zn-0.2Ca合金的细胞毒性.研究结果表明:Zn和Ca元素能够显著提高挤压态Mg-4.0Zn-0.2Ca合金在模拟体液中的抗腐蚀能力,减慢降解率;挤压态Mg-4.0Zn-0.2Ca合金与细胞的相容性良好,可用于骨种植.
研究瞭擠壓態Mg-4.0Zn-0.2Ca閤金的體外降解和細胞毒性,通過MTT法用L929細胞檢測擠壓態Mg-4.0Zn-0.2Ca閤金的細胞毒性.研究結果錶明:Zn和Ca元素能夠顯著提高擠壓態Mg-4.0Zn-0.2Ca閤金在模擬體液中的抗腐蝕能力,減慢降解率;擠壓態Mg-4.0Zn-0.2Ca閤金與細胞的相容性良好,可用于骨種植.
연구료제압태Mg-4.0Zn-0.2Ca합금적체외강해화세포독성,통과MTT법용L929세포검측제압태Mg-4.0Zn-0.2Ca합금적세포독성.연구결과표명:Zn화Ca원소능구현저제고제압태Mg-4.0Zn-0.2Ca합금재모의체액중적항부식능력,감만강해솔;제압태Mg-4.0Zn-0.2Ca합금여세포적상용성량호,가용우골충식.
The in-vitro degradation and in-vitro cytotoxicity of the as-extruded Mg-4.0Zn-0.2Ca alloy were investigated.The in-vitro corrosion tests indicate that Zn and Ca elements can dramatically increase the corrosion potential of the as-extruded Mg-4.0Zn-0.2Ca alloy in the simulated body fluid and reduce the degradation rate.The cytotoxicity of the as-extruded Mg-4.0Zn-0.2Ca alloy examined by MTT tests on L929 cells suggest that the alloy has eligible toxicity for implant applications.