CAJ | 학술논문

目的探讨快速旋转调强(RapidArc)计划和固定野调强计划(IMRT)的优劣.方法选择10例宫颈癌病例,在Eclipse 8.6计划系统上分别对其进行单弧、双弧及三弧RapidArc和固定野凋强放疗计划设计,依次分别用Arc 1、Arc 2、Arc 3和IMRT表示.比较4者的计划制作及治疗时间、靶区及危及器官剂量分布差异.结果 10例病例的Arc 1、Arc 2、Arc 3和IMRT计划设计时间平均值分别为112、131、154和46 min,在瓦里安IX加速器上的治疗时间平均值分别为2.15、3.32、4.48和6.95 min,平均剂量分别为48.99、49.40、49.51和48.65 Gy,靶区均匀指数分别为1.11、1.07、1.06和1.12,靶区适形指数分别为0.73、0.87、0.87和0.79.IMRT计划的直肠、膀胱和小肠等危及器官受量最小,4种计划的股骨颈受量相似.结论 RapidArc计划在靶区剂量分布、均匀度、适形度以及治疗时间方面占优势,IMRT计划在计划的剂量计算时间和危及器官的保护方面占优势.总体临床应用上RapidArc计划优于IMRT计划.
목적 탐토쾌속선전조강(RapidArc)계화화고정야조강계화(IMRT)적우렬.방법 선택10례궁경암병례,재Eclipse 8.6계화계통상분별대기진행단호、쌍호급삼호RapidArc화고정야조강방료계화설계,의차분별용Arc 1、Arc 2、Arc 3화IMRT표시.비교4자적계화제작급치료시간、파구급위급기관제량분포차이.결과 10례병례적Arc 1、Arc 2、Arc 3화IMRT계화설계시간평균치분별위112、131、154화46 min,재와리안IX가속기상적치료시간평균치분별위2.15、3.32、4.48화6.95 min,평균제량분별위48.99、49.40、49.51화48.65 Gy,파구균균지수분별위1.11、1.07、1.06화1.12,파구괄형지수분별위0.73、0.87、0.87화0.79.IMRT계화적직장、방광화소장등위급기관수량최소,4충계화적고골경수량상사.결론 RapidArc계화재파구제량분포、균균도、괄형도이급치료시간방면점우세,IMRT계화재계화적제량계산시간화위급기관적보호방면점우세.총체림상응용상RapidArc계화우우IMRT계화.
Objective To explore the advantages and disadvantages between the RapidArc plans and fixed-field IMRT plan (IMRT).Methods Ten cases of cervical cancer,aged 55 (36-70),who were to receive post-operative radiotherapy were selected randomly.Single arc (Arc 1),two arcs (Arc 2),and three arc (Arc 3) RapidArc plans and fixed-field IMRT plan were designed respectively in the Eclipse 8.6 planning system.The designing,treatment time,target area,and dose distribution of organs at risk by these 4 planning techniques were compared.Results The values of average planned treatment time by the Arc 1,Arc 2,and Arc 3 ten cases was 98,155,185,and 46 min,respectively.The values of average treatment time in the Varian IX accelerator were 2.15,3.32,4.48,and 6.95 min,respectively.The average mean doses were (48.99±1.08),(49.40±0.51) ,(49.51±0.62) ,and (48.65±0.92) Gy,respectively.The values of homogeneity index (HI) of target were 1.11±0.07,1.07±0.02,1.06±0.02,and 1.12±0.05,respectively.The values of eonformal index (CI) of target were 0.73±0.13,0.87±0.06,0.87±0.06,and 0.79±0.06,respectively.The doses at rectum,bladder,and small intestine calculated by IMRT plan were the lowest,and the doses at the femoral neck calculated by these 4 plans were similar.Conclusions The RapidArc plan is superior in dose distribution at target,HI,CI,and treatment time to IMRT,but IMRT plan is superior to RapidArc in planned dose calculation time and protection of organs at risk.However,in general,the RapidArc plan is better in clinical application than IMRT plan.