中华航海医学与高气压医学杂志
中華航海醫學與高氣壓醫學雜誌
중화항해의학여고기압의학잡지
CHINESE JOURNAL OF NAUTICAL MEDICINE AND HYPERBARIC MEDICINE
2012年
3期
147-150
,共4页
陆中元%陈兵%朱震%张骏%李雄伟%陆昕冶
陸中元%陳兵%硃震%張駿%李雄偉%陸昕冶
륙중원%진병%주진%장준%리웅위%륙흔야
胸部开放伤%海水浸泡伤%胸腔灌洗%血浆渗透压
胸部開放傷%海水浸泡傷%胸腔灌洗%血漿滲透壓
흉부개방상%해수침포상%흉강관세%혈장삼투압
Open chest injury%Injury induced by seawater immersion%thoracic lavage%Plasma osmotic pressure
目的 探讨加用胸腔灌洗法对犬海水浸泡胸部开放伤的治疗效果.方法 采用数字表法将成年杂交犬随机分为实验组(胸腔灌洗组)和对照组(常规救治组),每组10只,制成海水浸泡胸部开放伤动物模型.对照组采用常规救治,实验组在常规救治的基础上给予胸腔灌洗.观察2组部分血生化指标及肺组织病理改变的情况.结果 伤后1.0 h,对照组血清钠为(157.80±3.70) mmol/L,实验组为(146.25±4.14) mmol/L,2组比较差异有统计学意义(P＜0.05)；对照组渗透压为(345.46±6.18)mmol/L,实验组为(320.53±6.91) mmol/L,2组比较差异有统计学意义(P＜0.05)；在伤后8 h,对照组血清钠为( 146.80±2.87) mmol/L,实验组为(138.50±3.21) mmol/L,2组比较差异有统计学意义(P＜0.05)；对照组渗透压为(331.42±4.68)mmol/L,实验组为(312.24±5.23)mmol/L,2组比较差异有统计学意义(P＜0.01).海水浸泡胸部开放伤后,2组血清钠及血浆渗透压明显升高,经过治疗血清钠及血浆渗透压均降低,其中实验组的改善更明显,实验组肺组织的病理改变程度也小于对照组.结论 加用胸腔灌洗法是一种治疗海水浸泡胸部开放伤的有效方法.
目的 探討加用胸腔灌洗法對犬海水浸泡胸部開放傷的治療效果.方法 採用數字錶法將成年雜交犬隨機分為實驗組(胸腔灌洗組)和對照組(常規救治組),每組10隻,製成海水浸泡胸部開放傷動物模型.對照組採用常規救治,實驗組在常規救治的基礎上給予胸腔灌洗.觀察2組部分血生化指標及肺組織病理改變的情況.結果 傷後1.0 h,對照組血清鈉為(157.80±3.70) mmol/L,實驗組為(146.25±4.14) mmol/L,2組比較差異有統計學意義(P＜0.05)；對照組滲透壓為(345.46±6.18)mmol/L,實驗組為(320.53±6.91) mmol/L,2組比較差異有統計學意義(P＜0.05)；在傷後8 h,對照組血清鈉為( 146.80±2.87) mmol/L,實驗組為(138.50±3.21) mmol/L,2組比較差異有統計學意義(P＜0.05)；對照組滲透壓為(331.42±4.68)mmol/L,實驗組為(312.24±5.23)mmol/L,2組比較差異有統計學意義(P＜0.01).海水浸泡胸部開放傷後,2組血清鈉及血漿滲透壓明顯升高,經過治療血清鈉及血漿滲透壓均降低,其中實驗組的改善更明顯,實驗組肺組織的病理改變程度也小于對照組.結論 加用胸腔灌洗法是一種治療海水浸泡胸部開放傷的有效方法.
목적 탐토가용흉강관세법대견해수침포흉부개방상적치료효과.방법 채용수자표법장성년잡교견수궤분위실험조(흉강관세조)화대조조(상규구치조),매조10지,제성해수침포흉부개방상동물모형.대조조채용상규구치,실험조재상규구치적기출상급여흉강관세.관찰2조부분혈생화지표급폐조직병리개변적정황.결과 상후1.0 h,대조조혈청납위(157.80±3.70) mmol/L,실험조위(146.25±4.14) mmol/L,2조비교차이유통계학의의(P＜0.05)；대조조삼투압위(345.46±6.18)mmol/L,실험조위(320.53±6.91) mmol/L,2조비교차이유통계학의의(P＜0.05)；재상후8 h,대조조혈청납위( 146.80±2.87) mmol/L,실험조위(138.50±3.21) mmol/L,2조비교차이유통계학의의(P＜0.05)；대조조삼투압위(331.42±4.68)mmol/L,실험조위(312.24±5.23)mmol/L,2조비교차이유통계학의의(P＜0.01).해수침포흉부개방상후,2조혈청납급혈장삼투압명현승고,경과치료혈청납급혈장삼투압균강저,기중실험조적개선경명현,실험조폐조직적병리개변정도야소우대조조.결론 가용흉강관세법시일충치료해수침포흉부개방상적유효방법.
Objective To explore therapeutic effects of thoracic lavage for the treatment of open chest injury coupled with seawater immersion in dogs.Methods Adult mongrel dogs were randomly divided into the experimental group (the thoracic lavage group) and the control group (the routine treatment group),each consisting of 10 dogs.The animal model of open chest injury coupled with seawater immersion was developed in the laboratory.The control group received routine medical treatment,while the experimental group was administered with thoracic lavage in addition to routine medical treatment.Pathological changes in the internal environment and pulmonary tissues of the animals in the 2 groups were observed.Results One hour after injury,serum sodium of the control group was ( 157.80 ± 3.70 ) mmol/L,and that of the experimental group was (146.25 ±4.14) mmol/L (P＜0.05).Osmotic pressure of the control group was (345.46 ±6.18)mmol/L,and that of the experimental group was ( 320.53 ± 6.91 ) mmol/L ( P ＜ 0.05 ).Eight hours after injury,serum sodium of the control group was( 146.80 ± 2.87 ) mmol/L,and that of the experimental group was ( 138.5 ±3.21 ) mmol/L (P＜0.05).Osmotic pressure of the control group was (331.42 ±4.68) mmol/L,and that of the experimental group was ( 312.24 ± 5.23 ) mmol/L ( P ＜ 0.01 ).Following development of open chest injury coupled with seawater immersion,serum sodium and plasma osmotic pressure of both groups increased significantly.After treatment,serum sodium and plasma osmotic pressure of both groups all decreased,with the indices of the experimental group decreased more significantly.There were less pathological changes in the pulmonary tissue of the experimental group,when compared with the control group.Conclusions Thoracic lavage was effective for the treatment of open chest injury coupled with seawater immersion.
